The effect of genetic and enviromental factor to the development of bronchial asthma
| Project/Area Number |
23591534
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Gifu University |
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Principal Investigator |
MATSUI Eiko 岐阜大学, 医学部附属病院, 講師 (90334929)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | アレルギー / 環境因子 / 遺伝子 |
|---|
| Research Abstract |
The purpose of this research is to examine the interaction of the genetic and environmental factors with allergy disease. Therefore, detaile questionnaire of the environment factors before birth and after birth was corrected.Moreover, a lymphocyte surface marker and gene polymorphism were examined using umbilical cord blood and the peripheral blood.
When the episode of wheezing and the family history of bronchial asthma was positive, the rate of bronchial asthma was high by the follow-up to 3 years old.
In gene polymorphism, when ADRB2 (R16G) was AA type, the rate of bronchial asthma was high.
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Report
(4 results)
Research Products
(19 results)
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[Journal Article] Total IgE at 6 months predicts remittance or persistence of atopic dermatitis at 14 months2013
Author(s)
Kawamoto N, Fukao T, Kaneko H, Hirayama K, Sakurai S, Arai T MD, Kondo M, Kawamoto M, Matsui E, Orii K, Kasahara K, Takemura M, Seishima M, Shiraki M, Iwasa S, Kondo N
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Journal Title
Allergy Asthma Proc
Volume: 34
Pages: 362-369
Related Report
Peer Reviewed
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[Journal Article] Total IgE at 6 months predicts remittance or persistence of atopic dermatitis at 14 months.2013
Author(s)
Kawamoto N, Fukao T, Kaneko H, Hirayama K, Sakurai S, Arai T MD, Kondo M, Kawamoto M, Matsui E, Orii K, Kasahara K, Takemura M, Seishima M, Shiraki M, Iwasa S, Kondo N
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Journal Title
Allergy Asthma Proc
Volume: 34
Issue: 4
Pages: 362-369
DOI
Related Report
Peer Reviewed
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[Journal Article] Repeated-Dose Pharmacokinetics of Inhaled Ciclesonide (CIC-HFA) in Japanese Children with Bronchial Asthma : A Phase I Study2012
Author(s)
Teramoto T, Matsui E, Fukao T, Sakai K, Yonezawa H, Kato Z, Ohnishi H, Kaneko H, Kondo N, Azuma J, Nishima S.
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Journal Title
Allergol Int
Volume: 61
Pages: 619-624
NAID
Related Report
Peer Reviewed
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[Journal Article] Repeated-Dose Pharmacokinetics of Inhaled Ciclesonide (CIC-HFA) in Japanese Children with Bronchial Asthma: A Phase I Study.2012
Author(s)
Teramoto T, Matsui E, Fukao T, Sakai K, Yonezawa H, Kato Z, Ohnishi H, Kaneko H, Kondo N, Azuma J, Nishima S
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Journal Title
Allergol Int.
Volume: 61
Pages: 619-624
NAID
Related Report
Peer Reviewed
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