| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
We examined the relationship between neurodegenerative diseases including argyrophilic grain disease (AGD) and late-onset schizophrenia-like psychotic disorders (LOSD; onset age>40 years of age). In all LOSD cases (compared to controls), the frequencies of Lewy body disease (LBD), AGD, and corticobasal degeneration (CBD) were 26.1% (11.3%), 21.7% (8.5%), and 4.3% (0.0%), respectively. The total frequency of LBD, AGD, and CBD was significantly higher in LOSD cases than in normal controls. In LOSD patients whose onset occurred at >65 years of age, the frequencies of LBD and AGD were 36.4% (19.4%) and 36.4% (8.3%), respectively, and AGD was significantly more frequent in LOSD patients than in normal controls. Given these findings, AGD may be associated with the occurrence of LOSD.
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