| Project/Area Number |
23591850
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Tokai University |
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Principal Investigator |
TAKEDA Atsuya 東海大学, 医学部, 非常勤教員 (80296699)
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| Co-Investigator(Kenkyū-buntansha) |
KUNIEDA Etsuo 東海大学, 医学部, 教授 (70170008)
FUJII Hirofumi 独立行政法人国立がん研究センター, 東病院臨床開発センター機能診断開発部, 部長 (80218982)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 体幹部定位放射線治療 / 非小細胞肺癌 / FDG-PET / SUVmax / 予後因子 / 定位放射線治療 |
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| Research Abstract |
SUVmax is an index of accumulation in FDG-PET, and is expected to be a prognostic factor of various cancer. However, it is a relative index and is affected by tumor size, respiratory movement, tumor background, instrument and so on. We made an experiment using moving phantom and tried to correct SUVmax modified with tumor size and respiratory movement. Next, availability of the corrected SUVmax was investigated on the treatment results data of stereotactic body radiotherapy for patients with non-small cell cancer.
As results, actual SUVmax and corrected SUVmax were correlated well with local control and disease-free control. However, corrected SUVmax was not shown to be more correlated with those outcomes.
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