Elucidation of the proliferative mechanism of liver cancer stem cell based on the study of embryonal stem cell
| Project/Area Number |
23591982
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Kanazawa University |
|---|
Principal Investigator |
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| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
|---|
| Keywords | Zfp57 / がん幹細胞 / Nanog |
|---|
| Research Abstract |
Zfp57 is required for the tumorigenicity and hematogenous metastaic ability of humoral cancer cell line by upregulating IGF2 expression and Zfp57 activates AKT through IGF2 signaling.
Zfp57 is over-expressed in several humoral cancer tissues and especially in liver metastasis of colorectal cancer.
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Report
(4 results)
Research Products
(3 results)
