| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
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| Research Abstract |
Human cranial bones are thought to originate from the cranial neural crest that plays important role for constructiong central nervous systems in the embryo. In this study, we have investigated human cranial bone marrow derived stem cell (hcBMSC) capacities for neural differentiation. We cultured BMSC under simulated microgravity conditions to facilitate functional recovery from neural injury.
We show that hcBMSC has potency to differentiate into neural lineages better than the BMSC deriverd from illiac bone, and would be a novel alternative source of autologous adult stem cells for neural regenerative therapy.
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