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Pain chronisity and attention control

Research Project

Project/Area Number 23592287
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionOsaka University

Principal Investigator

HAGIHIRA Satoshi  大阪大学, 医学部附属病院, 講師 (90243229)

Co-Investigator(Kenkyū-buntansha) NAKAE Aya  大阪大学, 大学院医学系研究科, 特任准教授 (60379170)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords痛み / ワーキングメモリ / 注意 / 鎮静 / 実験的痛み / 注意課題 / 中央実行系
Research Abstract

Substantial evidence revealed that pain perception and cognitive function was related each other. We conducted the research that shows the relationship of the working memory capacity and pain perception using a working memory task, which is one of the cognitive task. Subjective pain intensity decreased in the memory task condition compared to no-task and control task condition (p <0.05) and % decrease was correlated with working memory capacity which was confirmed by the reading span task (r = 0.584, p <0.001).
There was no difference in memory task performance, but exhibited the same results in the control task performance as the pain intensity change. Our results revealed that the capacity in the brain related to information processing including pain perception might be limited. Therefore, in case that people had large working memory capacity, they had the ability to perform accurate evaluation of the pain simultaneously with the processing of the cognitive task.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (29 results)

All 2014 2013 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 1 results) Presentation (23 results) (of which Invited: 9 results) Book (2 results)

  • [Journal Article] Age-related and sex-related changes in perfusion index in response to noxious electrical stimulation in healthy subjects2014

    • Author(s)
      Toshiki Nishimura, Aya Nakae, Masahiko Shibata, Takashi Mashimo, Yuji Fujino
    • Journal Title

      J Pain Res

      Volume: 10 Pages: 91-97

    • Related Report
      2013 Final Research Report
  • [Journal Article] The influence of working memory capacity on experimental heat pain2013

    • Author(s)
      Aya Nakae, Kaori Endo, Tomonori Adachi, Takashi Ikeda, Satoshi Hagihira, Takashi Mashimo, Mariko Osaka
    • Journal Title

      J Pain

      Volume: 14 Pages: 1088-1096

    • Related Report
      2013 Final Research Report
  • [Journal Article] Pain modulation by negative and positive emotional sounds2013

    • Author(s)
      Aya Nakae, Thomas Hermann, Takashi Ikeda, Teruko Sakurai, Tomonori Adachi, Hiroshi Ito, Toshiki Nishimura, Masahiko Shibata, Mariko Osaka, Takashi Mashimo
    • Journal Title

      Proceedings of 4^<th> International Congress of Neuropathic pain

      Pages: 43-48

    • Related Report
      2013 Final Research Report
  • [Journal Article] ワーキングメモリの容量と実験的痛みの関係2011

    • Author(s)
      中江文、遠藤香織、安達友紀、奥知子、柴田政彦、苧阪満里子、真下節
    • Journal Title

      日本ペインクリニック学会誌

      Volume: 18(3) Pages: 338-338

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Correlation between changes of brain activity and subjective pain intensity under sedation ~Contact heat evoked potential study~2014

    • Author(s)
      Aya Nakae, Satoshi Hagihira, Hiroshi Ito, Piyasak Vitrabrananont, Kan Hongling, Yuji Fujino
    • Organizer
      Euroanaestheisa
    • Place of Presentation
      Stockholm
    • Year and Date
      2014-03-30
    • Related Report
      2013 Final Research Report
  • [Presentation] 鎮静下における痛み刺激に対する生理反応の違い。~プロポフォールとミダゾラムの比較~2014

    • Author(s)
      伊藤寛、中江文、康、紅玲、萩平哲、藤野裕士
    • Organizer
      第7回麻酔科痛みのメカニズムを語る会
    • Place of Presentation
      東京
    • Year and Date
      2014-03-05
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Invited
  • [Presentation] Contact heat evoked potentials (CHEPs) in healthy subjects–no laterality effect2014

    • Author(s)
      Yelena Granovsky, Praveen Anand, Aya Nakae, Osvaldo Nascimento, Benn Smith, Josep Valls-Sole, David Yarnitsky
    • Organizer
      30^<th> International Congress of Clinical Neurophysiology
    • Related Report
      2013 Final Research Report
  • [Presentation] The Influence of Age and Height on Latency and Amplitude of Contact Heat Evoked Potentials (CHEPS)2013

    • Author(s)
      Benn Smith, Yelena Granovsky, Osvaldo Nascimento, Josep Valls-Sole, Aya Nakae, David Yarnitsky, Huson L, Praveen Anand
    • Organizer
      American Neurological Association's 2013 Annual Meeting
    • Place of Presentation
      New Orleans, LA
    • Year and Date
      2013-10-15
    • Related Report
      2013 Final Research Report
  • [Presentation] ワーキングメモリにおける痛みの影響2013

    • Author(s)
      遠藤香織、中江文、藤野裕士、苧坂満里子
    • Organizer
      日本心理学会第77回大会
    • Place of Presentation
      札幌
    • Year and Date
      2013-09-21
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Pain and executive function. International Symposium on Cognitive Neuroscience Robotics2013

    • Author(s)
      Aya Nakae
    • Organizer
      Knowledge Theater
    • Place of Presentation
      Osaka
    • Year and Date
      2013-08-22
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Pain Modulation by Negative and Positive Emotional Sounds2013

    • Author(s)
      Aya Nakae, Thomas Hermann, Takashi Ikeda, Teruko Sakurai, Tomonori Adachi, Hiroshi Ito, Toshiki Nishimura, Masahiko Shibata, Mariko Osaka, Takashi Mashimo
    • Organizer
      4^<th>. INTERNATIONAL CONGRESS ON NEUROPATHIC PAIN(IASP)
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2013-03-24
    • Related Report
      2013 Final Research Report
  • [Presentation] Different effect of experimental electrical pain on autonomic nervous system derived from peripheral perfusion index in healthy volunteers2013

    • Author(s)
      Aya Nakae, Toshiki Nishimura, Masahiko Shibata, Takashi Mashimo, Yuji Fujino
    • Organizer
      8th Congress of the European Federation of IASP chapters-PAIN IN EUROPE VIII
    • Place of Presentation
      Florence
    • Related Report
      2013 Final Research Report
  • [Presentation] Pain and attention in elderly volunteers. International Symposium on Cognitive Neuroscience Robotics2013

    • Author(s)
      Aya Nakae
    • Organizer
      Paul G. Allen Center for CSE
    • Place of Presentation
      University of Washington, Seattle, Feb 1
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] ワーキングメモリの容量の大小の痛みの認知へのかかわり-Limited Capacity Modelの検証-2013

    • Author(s)
      中江文、遠藤香織、眞下節、苧坂満里子
    • Organizer
      日本ペインクリニック学会第47回大会
    • Place of Presentation
      大宮
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] C繊維の誘発電位の潜時に関する検討2013

    • Author(s)
      伊藤寛、康紅玲、中江文、柴田政彦、藤野裕士
    • Organizer
      第35回日本疼痛学会
    • Place of Presentation
      大宮
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Pain and executive function2013

    • Author(s)
      Aya Nakae
    • Organizer
      International Symposium on Cognitive Neuroscience Robotics
    • Place of Presentation
      大阪
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ワーキングメモリの容量の大小の痛みの認知へのかかわり-Limited Capacity Modelの検証-2013

    • Author(s)
      中江文、遠藤香織、眞下節、苧坂満里子
    • Organizer
      日本ペインクリニック学会第47回大会
    • Place of Presentation
      大宮
    • Related Report
      2013 Annual Research Report
  • [Presentation] 実験的痛みに対するワーキングメモリ個人差の影響2013

    • Author(s)
      中江 文
    • Organizer
      日本ペインクリニック学会第47回大会
    • Place of Presentation
      大宮
    • Related Report
      2012 Research-status Report
  • [Presentation] ワーキングメモリタスクの実験的痛みに対する影響2012

    • Author(s)
      中江文、遠藤香織、櫻井輝子、井上潤一、柴田政彦、苧坂満里子、眞下節
    • Organizer
      日本ペインクリニック学会第46回大会
    • Place of Presentation
      松江
    • Year and Date
      2012-07-07
    • Related Report
      2013 Final Research Report
  • [Presentation] The Influence of working memory task to experimental heat pain2012

    • Author(s)
      Aya Nakae, Kaori Endo, Teruko Sakurai, Masahiko Shibata, Mariko Osaka, Takashi Mashimo
    • Organizer
      14^<th> WORLD CONGRESS ON PAIN2012
    • Place of Presentation
      Milan, Italy
    • Related Report
      2013 Final Research Report
  • [Presentation] 実験的痛みと末梢循環の変化2012

    • Author(s)
      西村俊樹、中江文、柴田政彦、眞下節
    • Organizer
      第34回日本疼痛学会
    • Place of Presentation
      熊本
    • Related Report
      2013 Final Research Report
  • [Presentation] ワーキングメモリタスクの実験的痛みに対する影響2012

    • Author(s)
      中江 文
    • Organizer
      日本ペインクリニック学会第46回大会
    • Place of Presentation
      島根
    • Related Report
      2012 Research-status Report
  • [Presentation] The influence of working memory task to experimental heat pain2012

    • Author(s)
      Aya Nakae
    • Organizer
      国際疼痛学会
    • Place of Presentation
      ミラノ
    • Related Report
      2012 Research-status Report
  • [Presentation] ワーキングメモリの容量と実験的痛みの関係2011

    • Author(s)
      中江文、遠藤香織、安達友紀、奥知子、井上潤一、柴田政彦、苧阪満里子、眞下節
    • Organizer
      日本ペインクリニック学会第45回大会
    • Place of Presentation
      愛媛
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 情動と痛み、コメディカル講演会:痛みとアロマ2011

    • Author(s)
      中江文、眞下節
    • Organizer
      第33回日本疼痛学会
    • Place of Presentation
      愛媛
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 催眠による認知的評価と痛みの変化に関する研究2011

    • Author(s)
      安達友紀、中江文、柴田政彦、眞下節
    • Organizer
      第33回日本疼痛学会
    • Place of Presentation
      愛媛
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] ワーキングメモリの容量と実験的痛みの関係2011

    • Author(s)
      中江文、遠藤香織、安達友紀、奥知子、柴田政彦、苧阪満里子、真下節
    • Organizer
      日本ペインクリニック学会
    • Place of Presentation
      愛媛
    • Related Report
      2011 Research-status Report
  • [Book] "Mechanisms of Pain". Text book"Cognitive Neuroscience of Robotics"Chap.72014

    • Author(s)
      Aya Nakae.
    • Publisher
      (in press)
    • Related Report
      2013 Final Research Report
  • [Book] Cognitive Neuroscience Robotics2014

    • Author(s)
      Aya Nakae
    • Total Pages
      26
    • Publisher
      Elsevier
    • Related Report
      2013 Annual Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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