The development of new treatments for the flap survial and wound healing using fibrocyte or relevant stem cells.
| Project/Area Number |
23592649
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Plastic surgery
|
|---|
| Research Institution | Nagasaki University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
AKITA Sadanori 長崎大学病院, 形成外科, 講師 (90315250)
林田 健志 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 形成外科, 医師 (50599933)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
HAYASHIDA Kenji 長崎医療センター, 形成外科, 医師 (50599933)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | 幹細胞 / 創傷治癒 / リンパ浮腫動物モデル / 虚血肢動物モデル / ファイブロサイト / 皮弁生着 / 皮弁延長 |
|---|
| Research Abstract |
We have developed two new animal models of a lower extremity lymphedema mouse model and a lower extremity limb ischemia rat model. In the lymphedema model we confirmed regeneration of lymphatic vessels in the lymphedema model using adipose-derived stem cell transplantation. In the limb ischemia model we confirmed the improvement of blood circulation. We found to further improve blood circulation using combined adipose-derived stem cells and flap transplantation.
We think our two new animal models are available for the development of novel therapies using various stem cells and drug agents.
|
Report
(4 results)
Research Products
(29 results)
-
-
-
[Journal Article] One-stage simultaneous skin grafting with artificial dermis and basic fi broblast growth factor successfully improves elasticity with maturation of scar formation2013
Author(s)
Hamuy R, Kinoshita N, Yoshimoto H, H ayashida K, Houbara S, Nakashima M, Suzuki K, Mitsutake N, Mussazhanova Z, Kashiyama K, Hirano A, Akita S
-
Journal Title
Repair and Regene
Volume: 21(1)
Pages: 141-154
Related Report
Peer Reviewed
-
[Journal Article] One-stage, simultaneous skin grafting with artificial dermis and basic fibroblast growth factor successfully improves elasticity with maturation of scar formation.2013
Author(s)
Hamuy R, Kinoshita N, Yoshimoto H, Hayashida K, Houbara S, Nakashima M, Suzuki K, Mitsutake N, Mussazhanova Z, Kashiyama K, Hirano A, Akita
-
Journal Title
Wound Repair and Regeneration
Volume: 21(1)
Issue: 1
Pages: 141-154
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
