Development of the multipurpose adhesive system using Drug Delivery for Improved Direct pulp capping, Pulpotomy, and Periodontal treatment
| Project/Area Number |
23592822
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Kibi International University Junior College |
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Principal Investigator |
NAKAMURA Mariko 吉備国際大学短期大学部, 保健科, 教授 (90284067)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIDA Yasuhiro 北海道大学, 大学院歯学研究科, 教授 (90281162)
MATSUKAWA Akihiro 岡山大学, 大学院医歯(薬)学総合研究科, 教授 (90264283)
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| Co-Investigator(Renkei-kenkyūsha) |
ITO Yoshihiro 独立行政法人理化学研究所, 伊藤ナノ医工学研究室 (40192497)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | リン酸化プルラン / 可視光硬化型ゼラチン |
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| Research Abstract |
The purpose of this study is to develop a multi-purpose bio-adhesive system by the visible light-induced crosslinkable geratin and phosphorylated pullulan. The following things were confirmed from these findings. Phosphorylated pullulan-based composite is adhesive to dentin and possesses high biocompatibility. The visible light-induced crosslinkable gelatin is adhesive to dentin and low cellular toxicity. It was suggested that the visible light-induced crosslinkable gelatin and phosphorylated pullulan can be used as key materials of biodegradable adhesives for regeneration and reconstruction of bone and tooth.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] Mussel-inspired human gelatin nanocoating for creating biologically adhesive surfaces2014
Author(s)
Yang, X., Zhu, L., Tada, S., Zhou, D., Kitajima, T., Isoshima, T., Yoshida, Y., Nakamura, M., Yan, W., Ito, Y
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Journal Title
International Journal Nanomedicine
Volume: 29
Pages: 2753-2765
DOI
Related Report
Peer Reviewed
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[Journal Article] A novel, visible light-induced, rapidly cross-linkable gelatin scaffold for osteochondral tissue engineering2014
Author(s)
Tetsuro Mazaki, Yasuyuki Shiozaki, Kentaro Yamane, Aki Yoshida, Mariko Nakamura, Yasuhiro Yoshida, Di Zhou, Takashi Kitajima, Masato Tanaka, Yoshihiro ito, Toshifumi Ozaki, and Akihiro Matsukawa
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Journal Title
Sci. Rep.
Volume: 4
Issue: 1
Pages: 4457-4457
DOI
NAID
Related Report
Peer Reviewed
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[Journal Article] A novel, visible light-induced, rapidly cross-linkable gelarin scaffold for osteochondral tissue engineering2014
Author(s)
Mazaki, T., Shiozaki, Y., Yamane, K., Yoshida, A., Nakamura, M., Yoshida, Y., Zhou, D., Kitajima, T., Tanaka, M., Ito, Y., Ozaki, T., Matsukawa, A.
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Journal Title
Scientific Reports
Volume: 4
Related Report
Peer Reviewed
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[Patent(Industrial Property Rights)] 生体硬組織接着用キット2013
Inventor(s)
吉田靖弘, 田中雅人, 鈴木一臣, 尾崎敏文, 高畑智宏, 入江正郎, 中村真理子, 河島光伸, 野尻大和, 岡田浩一, 長尾昌浩
Industrial Property Rights Holder
国立大学法人岡山大学, 学校法人順正学園
Industrial Property Rights Type
特許
Filing Date
2013-01-11
Related Report
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