• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Gastric emptying rate in subjects with malocclusion examined by [13C] breath test

Research Project

Project/Area Number 23593023
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

FUKUYAMA Eiji  東京医科歯科大学, 歯学部, 非常勤講師 (60326064)

Co-Investigator(Kenkyū-buntansha) SHIMAZAKI Kazuno  東京医科歯科大学, 歯学部附属病院, 助教 (10420259)
ONO Takashi  東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (30221857)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Keywords胃排出機能 / 国際研究者交流
Research Abstract

Masticatory function is significantly lower in individuals with malocclusion than in those with normal occlusion. Although several studies suggest that masticatory function influences gastrointestinal digestive function, the relationship between malocclusion and gastrointestinal symptoms has not been studied extensively. We hypothesized that insufficient masticatory function would increase the functional burden of the stomach and have some influence on the gastrointestinal system. The purpose of this study was to investigate masticatory function and gastric emptying rate in subjects with malocclusion. Eleven healthy dentate female volunteers and eleven female patients with malocclusion underwent a 13C-acetate breath test with a liquid meal. Maximum 13CO2 exhalation time (Tmax) was compared statistically between both groups. The mean Tmax of the malocclusion group was significantly longer than that of the normal occlusion group.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (42 results)

All 2013 2012 2011

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (34 results) Book (1 results)

  • [Journal Article] Gastric emptying rate in subjects with malocclusion examined by [13C] breath test2013

    • Author(s)
      Koike S, Sujino T, Ohmori H, Shimazaki K, Fukuyama E, Kanai T, Hibi T, Ono T
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 40巻8号 Pages: 574-581

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gastric emptying rate in subjects with malocclusion examined by [13C] breath test2013

    • Author(s)
      Koike S, Sujino T, Ohmori H, Shimazaki K, Fukuyama E, Kanai T, Hibi T, Ono T.
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 40 Pages: 574-581

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Application of MRI movie for observation of articulatory movement during a fricative /s/ and a plosive /t/.2011

    • Author(s)
      Ng IW, Ono T, Inoue-Arai MS, Honda E, Kurabayashi T, Moriyama K.
    • Journal Title

      Angle Orthod

      Volume: 81 Pages: 237-244

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Functional adaptability of temporomandibular joint mechanoreceptors after an increase in the occlusal vertical dimension in rats.2011

    • Author(s)
      Naito S, Ishida T, Kokai S, Fujita K, Shibata M, Yabushita T, Ono T
    • Journal Title

      Angle Orthod

      Volume: 81 Pages: 243-249

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Intermittent posterior displacement of the rat mandible in the growth period affects the condylar cancellous bone.2011

    • Author(s)
      Kuroda Y, Yonemitsu I, Hosomichi J, Watari I, Takei M, Ishida Y, Ono T.
    • Journal Title

      Angle Orthod.

      Volume: 81 Pages: 975-82

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of sympathetic nervous activity on alveolar bone loss induced by occlusal hypofunction in rats.2011

    • Author(s)
      Shimizu Y, Hosomichi J, Kaneko S, Shibutani N, Ono T.
    • Journal Title

      Arch Oral Biol.

      Volume: 56 Pages: 1404-11

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Changes in the microstructure of the rat alveolar bone induced by unilateral molar extraction and estrogen deficiency.2011

    • Author(s)
      Honda K, Watari I, Takei M, Ono T.
    • Journal Title

      Orthod Waves.

      Volume: 70 Pages: 143-150

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Influence of masticatory disorder with malocclusion on gastric emptying2012

    • Author(s)
      Sarina Koike, Hiroko Ohmori, Kazuo Shimazaki, Eiji Fukuyama, Takashi Ono
    • Organizer
      88th CONGRESS EOS
    • Place of Presentation
      Santiago de Compostela (Spain)
    • Related Report
      2013 Final Research Report
  • [Presentation] 不正咬合は胃腸機能を低下する2012

    • Author(s)
      小池紗里奈、筋野智久、大森浩子、島﨑一夫、福山英治、金井隆典、日比紀文、小野卓史
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡
    • Related Report
      2013 Final Research Report
  • [Presentation] Influence of masticatory disorder with malocclusion on gastric emptying2012

    • Author(s)
      Sarina Koike, Hiroko Ohmori, Kazuo Shimazaki, Eiji Fukuyama, Takashi Ono
    • Organizer
      88TH CONGRESS OF THE EUROPEAN ORTHODONTIC SOCIETY
    • Place of Presentation
      Santiago de Compostela・Spain
    • Related Report
      2012 Research-status Report
  • [Presentation] 不正咬合は胃腸機能を低下する2012

    • Author(s)
      小池紗里奈、大森浩子、島﨑一夫、福山英治、小野卓史
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡・日本
    • Related Report
      2012 Research-status Report
  • [Presentation] 口蓋裂言語聴取時における聴覚連合野の脳賦活パタン:fMRIを用いた研究.2011

    • Author(s)
      疋田理奈、小野卓史、宮本順、誉田栄一、倉林亨、森山啓司.
    • Organizer
      第35回日本口蓋裂学会総会・学術大会
    • Place of Presentation
      新潟
    • Related Report
      2011 Research-status Report
  • [Presentation] 口唇口蓋同時形成術施行後の両側性唇顎口蓋裂(BCLP)患児2名に対して使用した上顎前方牽引装置の効果.2011

    • Author(s)
      米満郁男、藤田紘一、島崎一夫、渋谷直樹、君塚幸子、尾崎周作、福山英治、長西裕樹、小野卓史、大村進、藤内祝、鳥飼勝行
    • Organizer
      第35回日本口蓋裂学会総会・学術大会
    • Place of Presentation
      新潟
    • Related Report
      2011 Research-status Report
  • [Presentation] 骨格性下顎前突症における上下顎同時移動術前後の咽頭部気道形態の評価.2011

    • Author(s)
      藤田紘一、米満郁男、島崎一夫、渋谷直樹、君塚幸子、小澤知倫、尾崎周作、福山英治、小野卓史、大村進、藤内祝.
    • Organizer
      第21回日本顎変形症学会総会・30周年記念国際シンポジウム
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] Differential response properties of the human periodontal-masseteric reflex of the anterior teeth.2011

    • Author(s)
      Ohmori H, Kirimoto H, Ono T.
    • Organizer
      87th Congress of the European Orthodontic Society,
    • Place of Presentation
      Istanbul
    • Related Report
      2011 Research-status Report
  • [Presentation] Effects of low masticatory loading on the response properties of TMJ-nociceptors in growing rats.2011

    • Author(s)
      Hiranuma M, Kokai S, Fujita K, Yabushita T, Ono T
    • Organizer
      87th Congress of the European Orthodontic Society
    • Place of Presentation
      Istanbul
    • Related Report
      2011 Research-status Report
  • [Presentation] Functional adaptability of temporomandibular joint mechanoreceptors after an increase in the occlusal vertical dimension in rats.2011

    • Author(s)
      Naito S, Ishida T, Kokai S, Yabushita T, Ono T.
    • Organizer
      87th Congress of the European Orthodontic Society
    • Place of Presentation
      Istanbul
    • Related Report
      2011 Research-status Report
  • [Presentation] Mechanical stress on the periodontium influences on the expression of aquaporin 5 in the rat submandibular and sublingual salivary glands.2011

    • Author(s)
      Mizumachi M, Watari I, Ishida Y, Ono T.
    • Organizer
      87th Congress of the European Orthodontic Society,
    • Place of Presentation
      Istanbul
    • Related Report
      2011 Research-status Report
  • [Presentation] Effects of increased occlusal vertical dimension on motor representations within the face motor cortex of adult rats.2011

    • Author(s)
      Kato C, Fujita K, Kokai S, Yabushita T, Ono T.
    • Organizer
      87th Congress of the European Orthodontic Society,
    • Place of Presentation
      Istanbul
    • Related Report
      2011 Research-status Report
  • [Presentation] Treatment of an impacted mandibular lateral incisor and canine due to compound odontoma: A case report2011

    • Author(s)
      Shibutani N, Shimazaki K, Momozawa T, Mishimagi T, Ono T.
    • Organizer
      87th Congress of the European Orthodontic Society, Istanbul
    • Place of Presentation
      Istanbul
    • Related Report
      2011 Research-status Report
  • [Presentation] Mandibular hinge axis in skeletal class III posterior unilateral crossbite patients2011

    • Author(s)
      Shibutani N, Shimazaki K, Momozawa T, Mishimagi T, Ono T.
    • Organizer
      87th Congress of the European Orthodontic Society, Istanbul
    • Place of Presentation
      Istanbul
    • Related Report
      2011 Research-status Report
  • [Presentation] 喘息を有する成長期下顎前突症例:気道形態と下顎骨の成長に関する一考察.2011

    • Author(s)
      小海暁、簡野瑞誠、小野卓史.
    • Organizer
      第70回東京矯正歯科学会大会
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] 反対咬合改善後に投与された蛋白同化ホルモンにより著明な下顎前方成長が誘発された1症例2011

    • Author(s)
      若杉絵美奈、渡一平、石田雄之、小野卓史.
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 咬合刺激低下は歯根膜血管新生の抑制を介して矯正学的な歯の移動に影響を与える.2011

    • Author(s)
      臼見莉沙、小野法明、細道純、渋谷直樹、金香佐和、小野卓史.
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 咬合高径増加がラット大脳皮質一次運動野顎顔面領域における機能局在に与える影響2011

    • Author(s)
      加藤千帆、藤田紘一、藪下忠親、内藤聡美、柴田真衣、石田宝義、小海暁、小野卓史
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 骨格性下顎前突症患者に対する異なる外科手術法が上部気道形態に与える影響.2011

    • Author(s)
      水町真理子、渡一平、石田雄之、小野卓史.
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 前歯部におけるヒト歯根膜咬筋反射の応答特性の違いについて.2011

    • Author(s)
      大森浩子、桐本博章、小野卓史
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 超弾性型Ti-Ni合金ワイヤーを組み込んだ可撤式装置を用いた混合歯列期の片側性鋏状咬合症例2011

    • Author(s)
      大森浩子、福山英治、小野卓史.
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 術前矯正治療中に一時的な下歯槽神経麻痺が出現した骨格性開咬症例2011

    • Author(s)
      渡一平、米満郁男、藤田紘一、小澤知倫、渋谷直樹、君塚幸子、大村進、小野卓史
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 外科的矯正治療に伴う咬合平面の反時計方向への回転によって顔貌の改善を図った小下顎症の一例2011

    • Author(s)
      島崎一夫、米満郁男、藤田紘一、渋谷直樹、大村進、藤内祝、小野卓史
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 重度の叢生による下顎両側小臼歯の半埋伏および過蓋咬合を伴う成人非抜歯症例2011

    • Author(s)
      簡野瑞誠、小野卓史.
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 著しい咬合崩壊を伴う成人唇顎口蓋裂患者に対して欠損補綴を用いず咬合再構成した一例.2011

    • Author(s)
      福山英治、大村進、君塚幸子、島崎一夫、米満郁男、藤田紘一、藤内祝、小野卓史
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] Severe root resorption of four maxillary incisors and bilateral canine impaction: An interdisciplinary approach.2011

    • Author(s)
      Matsumoto Y, Takahashi Y, Soma K, Ono T
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 咬みしめに伴う上肢筋の促通とそれに同期した脳賦活パタン:fMRIを用いた研究2011

    • Author(s)
      川久保直美、小野卓史、宮本順、誉田栄一、倉林亨、森山啓司
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 口輪筋訓練における口輪筋筋活動および血流量の同時計測の有用性2011

    • Author(s)
      出井彩乃、宮本順、高田潤一、小野卓史、森山啓司
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 舌触覚刺激に対する2点弁別および大脳皮質賦活パタンにおける習慣性咀嚼側の関与2011

    • Author(s)
      湊亜紀子、宮本順、小野卓史、誉田栄一、倉林亨、森山啓司.
    • Organizer
      第70回日本矯正歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] A case of unilateral CLP with overclosure treated by maxillary distraction osteogenesis using internal devices.2011

    • Author(s)
      Kaneko S, Fukuyama E, Shimazaki K, Ono T.
    • Organizer
      Korean Association of Orthodontists
Annual Scientific Congress,
    • Place of Presentation
      Seoul, Korea,
    • Related Report
      2011 Research-status Report
  • [Presentation] Relationship between the ratio of adenoid/tonsillar tissues for the pharyngeal airway and cephalometric variables.2011

    • Author(s)
      Yoon HS, Ishida T, Ono T.
    • Organizer
      Korean Association of Orthodontists
Annual Scientific Congress,
    • Place of Presentation
      Seoul, Korea,
    • Related Report
      2011 Research-status Report
  • [Presentation] 各種金属材料を用いたMRIアーチファクトの3次元的評価.(ポスター発表)2011

    • Author(s)
      野村直之、堤祐介、土居壽、塙隆夫、今井治樹、田中洋次、小野卓史、大野喜久郎.
    • Organizer
      第149回日本金属学会
    • Place of Presentation
      宜野湾
    • Related Report
      2011 Research-status Report
  • [Presentation] 各種金属材料を用いたMRIアーチファクトの3次元的評価2011

    • Author(s)
      今井治樹、田中洋次、野村直之、堤祐介、土居壽、大野喜久郎、小野卓史、塙隆夫
    • Organizer
      回日本バイオマテリアル学会
    • Place of Presentation
      広島
    • Related Report
      2011 Research-status Report
  • [Presentation] 成長期の下顎骨機能的偏位が顎関節潤滑能に与える影響について2011

    • Author(s)
      服部育子、渡一平、武居真希、石田雄之、米満郁男、小野卓史
    • Organizer
      第76回口腔病学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Book] Type 1 Diabetes Complications/ ISBN2011

    • Author(s)
      Abbassy MA, Watari I, Ono T.
    • Publisher
      The effect of type 1 Diabetes Mellitus on the craniofacial complex.
    • Related Report
      2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi