Gastric emptying rate in subjects with malocclusion examined by [13C] breath test
| Project/Area Number |
23593023
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
FUKUYAMA Eiji 東京医科歯科大学, 歯学部, 非常勤講師 (60326064)
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| Co-Investigator(Kenkyū-buntansha) |
SHIMAZAKI Kazuno 東京医科歯科大学, 歯学部附属病院, 助教 (10420259)
ONO Takashi 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (30221857)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 胃排出機能 / 国際研究者交流 |
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| Research Abstract |
Masticatory function is significantly lower in individuals with malocclusion than in those with normal occlusion. Although several studies suggest that masticatory function influences gastrointestinal digestive function, the relationship between malocclusion and gastrointestinal symptoms has not been studied extensively. We hypothesized that insufficient masticatory function would increase the functional burden of the stomach and have some influence on the gastrointestinal system. The purpose of this study was to investigate masticatory function and gastric emptying rate in subjects with malocclusion. Eleven healthy dentate female volunteers and eleven female patients with malocclusion underwent a 13C-acetate breath test with a liquid meal. Maximum 13CO2 exhalation time (Tmax) was compared statistically between both groups. The mean Tmax of the malocclusion group was significantly longer than that of the normal occlusion group.
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Report
(4 results)
Research Products
(42 results)
