| Project/Area Number |
23650296
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
HAGIHARA Yoshihisa 独立行政法人産業技術総合研究所, 健康工学研究部門, 研究グループ長 (50357761)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAJIMA Yoshihiro 独立行政法人産業技術総合研究所, 健康工学研究部門, 生体機能制御研究グループ長 (10291080)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 細胞 / 組織工学 / ペプチド / 蛋白質導入 / 細胞毒性 / iPS細胞 / フォールディング / 転写因子 / リプログラミング因子 / 生物発光 / 蛋白質工学 |
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| Research Abstract |
To improve efficiency of development of the piPS cell, we successfully constructed the cultured cell system to evaluate the transduction of purified transcription factor proteins into cell. Then, we synthesized honey bee venom toxin melittin analogues to
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