| Project/Area Number |
23650626
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical oncology
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| Research Institution | Hiroshima University |
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Principal Investigator |
TAHARA Hidetoshi 広島大学, 大学院・医歯薬学総合研究科, 教授 (00271065)
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| Co-Investigator(Renkei-kenkyūsha) |
OCHIYA Takahiro 独立行政法人国立がん研究センター, がん転移研究室, 室長 (60192530)
KURODA Masahiko 東京医科大学, 医学部, 教授 (80251304)
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| Project Period (FY) |
2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
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| Keywords | エクソソーム / マイクロRNA / ドラッグデリバリーシステム / がん / DDS |
|---|
| Research Abstract |
We have developed Cd44-GFP expressing cells including normal and cancer cell lines to visualized exosomes. We also purified CD44-GFP labeled exosomes form those cells. We confirmed that CD44-GFP labeled exosomes cargo microRNA by adding these exosomes to the other cells. These tools should be useful for exosome derived DDS technology.
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