| Project/Area Number |
23658163
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General fisheries
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 春季発動 / キスペプチン / 神経ペプチド / 春機発動 / Kiss / GnRH / GtH / マサバ |
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| Research Abstract |
Kisspeptins, encoded by kissgenes have emerged as critical regulator of reproductive function in vertebrates. In the present study, we evaluated the potency of Kiss1 and Kiss2 to induce pubertal onset in prepubertal chub mackerel. Gonadosomatic index (GSI) of Kiss1 treated fish increased significantly in comparison to other treatments. Histologically, 66.7% of Kiss1 treated fish exhibited presence of spermatozoa in the testes. However,Kiss2-12 treated fish showed only spermatocytes as the advanced germ cells in the testes. In contrast, only spermatogonia were observed in the testes of initial and untreated final control fish. Levels of sex steroids were significantly higher in Kiss1 treated fish. These results indicate application of Kiss1 peptides for accelerating pubertal onset in chub mackerel.
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