Preservation of endangered and rare animalspecies using induced pluripotent stem cells.
| Project/Area Number |
23658224
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied animal science
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| Research Institution | Kyoto University |
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Principal Investigator |
IMAI Hiroshi 京都大学, 大学院・農学研究科, 教授 (10303869)
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| Co-Investigator(Kenkyū-buntansha) |
OKADA Kounosuke 日本獣医生命科学大学, 応用生命科学部, 講師 (60445830)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 野生動物保護・増殖 / 多能性幹細胞 |
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| Research Abstract |
The establishment of induced pluripotent stem (iPS) cells in vole and the characterizations of the established cell lines hasbeen performed as a model experiment for the preservation of endangered and rare animal species. Pluripotent-related four transcription genes were introduced into somatic cells using retroviral vectors. Colonies like as mouse embryonic stem (ES) cells were obtained. These colonies have a part of stem cell potential, but have limited pluripotent characteristics. Further experiments are necessary to establish a system inducing nuclear reprogramming of somatic cells in vole.
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Report
(3 results)
Research Products
(15 results)
