| Project/Area Number |
23658225
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied animal science
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 応用動物 / 畜産学 / 雄性繁殖能力 / 精子 / 人工授精 / 凍結保存 / 精子凍結保存 / リン酸化タンパク質 / 精巣上体 / 膜安定化因子 |
|---|
| Research Abstract |
There are great differences in the freezability of mammalian spermatozoa among species. In cattle, high freezability of the spermatozoa enables us to use frozen semen in the AI program. In this study, we indicated the molecular mechanism for epididymal maturation-related stabilization of the plasma membrane which brings high freezability to bull spermatozoa. In addition, we attempted to develop in vitro incubation system to enhance sperm freezability on the basis of the above-mentioned molecular mechanism.
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