| Project/Area Number |
23659360
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Public health/Health science
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
SANO HIRONARI 東京慈恵会医科大学, 医学部, 講師 (20408404)
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 網膜病変 / 境界型糖尿病 / 高齢者 / 地域調査 / 疫学 / 生活習慣病 / 地域調査研究 |
|---|
| Outline of Final Research Achievements |
Out of 1,752 subjects aged 40 and over, we selected 622 subjects aged 65 and over, who had a high possibility of having borderline diabetes. Retinal lesion was observed in 95 cases. The number of 17 cases of epiretinal membrane lesion was the largest, followed by 13 cases of fundus hypertonicus or hypertensive retinopathy, 13 cases of retinal bleeding, and 13 cases of retinal atrophy. Retinal lesion was observed in 15.3% of those aged 65 and over, and this rate was significantly higher (P<0.01) when compared to the rate of 7.7% among those aged 40-64. In our study of background factors affecting retinal lesion, it was suggested that the disease among those aged 40-64 might be related to systolic blood pressure whereas retinal lesion among the elderly aged 65 and over might be related to systolic blood pressure and body mass index.
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