| Project/Area Number |
23659582
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
MAGATA Yasuhiro 浜松医科大学, メディカルフォトニクス研究センター, 教授 (20209399)
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| Co-Investigator(Kenkyū-buntansha) |
SAKAHARA Harumi 浜松医科大学, 医学部, 教授 (10187031)
SAKAI Toshihiro 浜松医科大学, メディカルフォトニクス研究センター, 特任研究員 (40585098)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 放射線内用療法 / 分子標的薬 / イメージング / 放射性医薬品 / がん / I-131 / 分子標的 / 低分子 / EGFR-TK |
|---|
| Research Abstract |
This study is a trial to develop a novel concept which makes molecular target drug for cancer enable radiation therapy . This concept can allow not only molecular target imaging and also molecular target radiation therapy. In this study, we use our new molecular imaging compound, PYK for EGFR-TK. This compound has a great potential for in vivo imaging for EGFR-TK. In conclusion, molecular target radiation therapy might be achieved although additional compounds are required to improve target uptake or target to non-target ratio.
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