Development of animal model with esophageal atresia
Project/Area Number |
23659824
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Pediatric surgery
|
Research Institution | Jichi Medical University |
Principal Investigator |
ONO Shigeru 自治医科大学, 医学部, 准教授 (00315962)
|
Co-Investigator(Kenkyū-buntansha) |
SASAKI Yasunari 京都府立医科大学, 医学研究科, その他 (30405253)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 先天性食道閉鎖症 / 動物モデル / 食道閉鎖症 / レチノイン酸 / 食道閉鎖症モデル |
Research Abstract |
The aim of this study is the development of animal model with esophageal atresia to develop a new treatment procedure including surgical technique. We tried to develop rabbit model with esophageal atresia using oral administration of Retinoic acid. Variety of doses of all-trans Retinoic acid were administrated, however no anomaly including esophageal atresia were observed excepting some melting fetus.
|
Report
(4 results)
Research Products
(2 results)