| Project/Area Number |
23659838
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | Nippon Medical School |
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Principal Investigator |
ISHII Nobuaki 日本医科大学, 医学研究科, 研究員 (00445826)
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| Co-Investigator(Kenkyū-buntansha) |
OGAWA Rei 日本医科大学, 医学部, 准教授 (70398866)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 組織培養 / 移植学 / ケロイド / 肥厚性瘢痕 / カルシウムイオンチャネル / 力学的刺激 / メカノバイオロジー / シグナル伝達 / 線維芽細胞 / イオンチャネル / Caイオンチャネル拮抗薬 / コラーゲン / 創傷治癒 |
|---|
| Research Abstract |
Ca ion channels are activated by mechanical forces such as hydrostatic pressure especially on chondrocytes in the articular cartilage. However, such ion channels are not significantly activated on fibroblasts in the skin.
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