| Project/Area Number |
23659897
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthetic dentistry
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| Research Institution | The University of Tokushima (2012)
Okayama University (2011) |
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Principal Investigator |
MATSUKA Yoshizo 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (90243477)
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| Co-Investigator(Kenkyū-buntansha) |
KUBOKI Takuo 岡山大学, 大学院・医歯薬学総合研究科, 教授 (00225195)
MATSUO Ryuji 岡山大学, 大学院・医歯薬学総合研究科, 教授 (30157268)
OGUMA Keiji 岡山大学, 大学院・医歯薬学総合研究科, 教授 (00002262)
YAMAMOTO Yumiko 岡山大学, 大学院・医歯薬学総合研究科, 助教 (20403496)
KUMADA Ai 岡山大学, 岡山大学病院, 医員 (40610895)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | ボツリヌス毒素 / 神経細胞 / 活性 / 長寿命化 / トレハロース / 海馬 / 三叉神経 |
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| Research Abstract |
Dissociated rat trigeminal ganglion somata were incubated with matrigel in 37℃ CO_2condition. Commercially available hippocampus neuron was used in this study. Neuronal change was observed and the neuron that incubated with type A Botulinum toxin was survived longer than control. Also, dendrite of the neuron with Rotulinum toxin was longer than control neuron.
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