Identification of allergens for metal allergy by hydrodynamic voltammetry.

• Project/Area Number: 23659927
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Matsumoto Dental University
• Principal Investigator: HORASAWA Noriko 松本歯科大学, 歯学部, 講師 (20165567)
• Research Collaborator: MIROSLAV Marek ジョージア工科大学, 材料工学, 教授
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 金属アレルギー / 回転リングディスク電極法 / アレルゲン / 対流ボルタンメトリー / タンパク質 / アミノ酸 / 金属イオン / 酸化-還元曲線 / 酸化－還元曲線 / 回転リングディスク電極 / ストリッピングボルタンメトリー

Research Abstract

It is said that the allergen for metal allergy is produced by the protein in human body and the released metal ions. However the kinds of protein in human body are too much. An amino acid is the smallest structured unit of protein. Therefore as first step, the reaction was investigated between the amino acid and metal.The aim of this study was to identify potential allergens for metal allergy. The electrochemical interaction between pure metals and amino acid was examined by hydrodynamic voltammetry.

Research Products

• [Presentation] Identification of allergens for metal allergy by hydrodynamic voltammetry (2012)
  • Author(s): 洞澤 功子(代表者)、Miroslav Marek
  • Organizer: 国際歯科研究学会日本部会(JADR)
  • Place of Presentation: 新潟市
• [Presentation] Identification of allergens for metal allergy by hydrodynamic voltammetry. (2012)
  • Author(s): 洞沢 功子(代表者）、Miroslav Marek
  • Organizer: 国際歯科研究学会日本部会（JADR)
  • Place of Presentation: 新潟コンベンションセンター（朱鷺メッセ）（新潟市）