Development of a fabrication method for a functionally collaborating cellular device utilizing stem cells
Project/Area Number |
23686119
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Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Single-year Grants |
Research Field |
Biofunction/Bioprocess
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Research Institution | Hiroshima University (2012-2013) Tokyo University of Agriculture and Technology (2011) |
Principal Investigator |
FUNABASHI Hisakage 広島大学, サステナブル・ディベロップメント実践研究センター, 特任講師 (60552429)
|
Project Period (FY) |
2011-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥22,100,000 (Direct Cost: ¥17,000,000、Indirect Cost: ¥5,100,000)
Fiscal Year 2013: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2012: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2011: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
|
Keywords | 細胞デバイス / 遺伝子発現制御 / 分化誘導 / 遺伝子発現解析 / イメージング解析 / インスリン / バイオセンサー / 生体機能利用 / ライブセルイメージング / mRNA検出 / 生体材料 / 生物・生体工学 / フェムトインジェクション / 単一細胞 |
Outline of Final Research Achievements |
In this research, we have developed “a basic technique for inducing cellular differentiation by the down regulation of the activity of a target transcription factor based on the evaluation of gene expression status in a target cell” and “a basic technique for online insulin monitoring which can be applied to the evaluation of cellular functional collaboration”. These two basic techniques are expected to be applied to a fabrication method for “a cellular device in which various types of cells derived from stems cells functionally collaborate”.
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Report
(4 results)
Research Products
(25 results)