Evolution of neo-mineral knowledge understanding CKD-MBD

• Project/Area Number: 23689045
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Kidney internal medicine
• Research Institution: The University of Tokushima
• Principal Investigator: SEGAWA Hiroko 徳島大学, ヘルスバイオサイエンス研究部, 講師 (70325257)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000); Fiscal Year 2013: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000); Fiscal Year 2012: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000); Fiscal Year 2011: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
• Keywords: リン利尿 / 腎臓 / 小腸 / 唾液腺 / トランスポーターランスポーター / CKD / MBD / CKD-MBD / Phosphate / Transporter / Kidney / Intestine / Saliva / 慢性腎臓病 / リン

Research Abstract

Hyperphosphatemia is contributes to vascular calcification in patients with chronic kidney disease and hemodialysis patients and is associated with cardiac mortality. Recently, several studies reported the relationship among salivary phosphate concentration, renal function, serum phosphate concentration, and the potential target of new therapy for hypephosphatemia. However, it is unclear the inorganic phosphate (Pi) handling mechanisms in salivary glands. In the present study, we investigated the Pi handling in salivary glands. In wild-type mice fed a high Pi diet, the levels of plasma and salivary Pi are significantly higher than those in mice fed a low Pi diet. In Npt2b+/- mice, the salivary Pi concentrations were significantly increased compared with those in Npt2b+/+ mice. The present study suggests that salivary Pi levels correlate with dietary Pi content, and salivary glands paly a role for phosphate homeostasis system in the body.

Research Products

• [Journal Article] Down-regulation of renal type IIa sodium-dependent phosphate co-transporter during lipopolysaccharide-induced acute inflammation (2014)
  • Author(s): Ikeda S, Yamamoto H, Masuda M, Miyamoto K(他9名)
  • Journal Title: Am J Physiol Renal Physiol Volume: 306(7) Issue: 7 Pages: 744-750
  • DOI: 10.1152/ajprenal.00474.2013
  • Peer Reviewed / Open Access
• [Journal Article] Effect of dietary components on renal inorganic phosphate (Pi) excretion induced by a Pi-depleted diet. (2014)
  • Author(s): Ohnishi R, Segawa H, Ohmoto T, Sasaki S, Hanazaki A, Mori A, Ikuta K, Furutani J, Kawakami E, Tatsumi S, Hamada Y, Miyamoto K
  • Journal Title: J Med Invest Volume: 61 Pages: 162-70
  • NAID: 130004822704
  • Peer Reviewed
• [Journal Article] Role of serine 249 of ezrin in the regulation of sodium-dependent phosphate transporter NaPi-IIa activity in renal proximal tubular cells (2013)
  • Author(s): Yamada F, Horie D, Nakamura A, Tanimura A, Yamamoto H, Segawa H, Ito M, Miyamoto K, Taketani Y, Takeda E
  • Journal Title: J Med Invest Volume: 60 Pages: 27-34
  • NAID: 130004465290
  • Peer Reviewed
• [Journal Article] Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute response to PTH (2013)
  • Author(s): Maeda A, Okazaki M, Baron DM, Dean T, Khatri A, Mahon M, Segawa H, Abou-Samra AB, Jüppner H, Bloch KD, Potts JT Jr, Gardella TJ
  • Journal Title: Proc Natl Acad Sci USA Volume: 110 Issue: 15 Pages: 5864-5869
  • DOI: 10.1073/pnas.1301674110
  • Peer Reviewed
• [Journal Article] Ezrin, a membrane cytoskeletal cross-linker, is essential for the regulation of phosphate and calcium homeostasis (2013)
  • Author(s): Hatano R, et al
  • Journal Title: Kidney Int Volume: Jan;83(1) Issue: 1 Pages: 41-49
  • DOI: 10.1038/ki.2012.308
  • Peer Reviewed
• [Journal Article] Activation of a non-cAMP/PKA signaling pathway downstream of the PTH/PTHrP receptor is essential for a sustained hypophosphatemic response to PTH infusion in male mice (2013)
  • Author(s): Guo J, Song L, Liu M, Segawa H, Miyamoto K, Bringhurst FR, Kronenberg HM, Jüppner H
  • Journal Title: Endocrinology Volume: 154 Issue: 5 Pages: 1680-1689
  • DOI: 10.1210/en.2012-2240
  • Peer Reviewed
• [Journal Article] Dietary inorganic phosphorus regulates the intestinal peptide transporter PepT1 (2013)
  • Author(s): Furutani J, Ito M, et al
  • Journal Title: J Ren Nutr Volume: 23(2):e11-20 Issue: 2 Pages: 1-20
  • DOI: 10.1053/j.jrn.2012.02.006
  • Peer Reviewed
• [Journal Article] Role of serine 249 of ezrin in the regulation of sodium-dependent phosphate transporter NaPi-IIa activity in renal proximal tubular cells. (2013)
  • Author(s): Yamada F, Horie D, Nakamura A, Tanimura A, Yamamoto H, Segawa H, Ito M, Miyamoto K, Taketani Y, Takeda E
  • Journal Title: J Med Invest Volume: 60 Pages: 27-34
  • NAID: 130004465290
  • Peer Reviewed
• [Journal Article] Fanconi-Bickel syndrome and autosomal recessive proximal tubulopathy with hypercalciuria (ARPTH) are allelic variants caused by GLUT2 mutations (2012)
  • Author(s): Mannstadt M, Magen D, Segawa H, Stanley T, Sharma A, Sasaki S, Bergwitz C, Mounien L, Boepple P, Thorens B, Zelikovic I, Juppner H
  • Journal Title: J Clin Endocrinol Metab Volume: 97 Issue: 10 Pages: E1978-E1986
  • DOI: 10.1210/jc.2012-1279
  • Peer Reviewed
• [Journal Article] Identification and functional analysis of a splice variant of mouse sodium-dependent phosphate transporter Npt2c (2012)
  • Author(s): Kuwahara S, Aranami F, Segawa H, Onitsuka A, Honda N, Tominaga R, Hanabusa E, Kaneko I, Yamanaka S, Sasaki S, Ohi A, Nomura K, Tatsumi S, Kido S, Ito M, Miyamoto K
  • Journal Title: J Med Invest Volume: 59 Pages: 116-126
  • NAID: 130004465255
  • Peer Reviewed
• [Journal Article] Processing and stability of type II sodium-dependent phosphate cotransporter mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria (2012)
  • Author(s): Haito-Sugino S, et al
  • Journal Title: Am J Physiol Cell Physiol Volume: (In press) Issue: 9 Pages: C1316-C1330
  • DOI: 10.1152/ajpcell.00314.2011
  • Peer Reviewed
• [Journal Article] Identification and functional analysis of a splice variant of mouse sodium-dependent phosphate transporter Npt2c (2012)
  • Author(s): Kuwahara S, et al
  • Journal Title: The Journal of Medical Investigation Volume: 59 Issue: 1,2 Pages: 116-126
  • DOI: 10.2152/jmi.59.116
  • NAID: 130004465255
  • ISSN: 1343-1420, 1349-6867
  • Peer Reviewed
• [Journal Article] Inorganic phosphate homeostasis in sodium-dependent phosphate co-transporter Npt2b+/- mice (2011)
  • Author(s): Ohi A, et al
  • Journal Title: Am J Physiol Renal Physiol Volume: 1 Issue: 5 Pages: F1105-F1113
  • DOI: 10.1152/ajprenal.00663.2010
  • Peer Reviewed
• [Journal Article] Acute down-regulation of sodium-dependent phosphate transporter NPT2a involves predominantly the cAMP/PKA pathway as revealed by signaling-selective parathyroid hormone analogs (2011)
  • Author(s): Nagai S, Okazaki M, Segawa H, Bergwitz C, Dean T, Potts JT Jr, Mahon MJ, Gardella TJ, Jüppner H
  • Journal Title: J. Biol. Chem Volume: 286 Issue: 2 Pages: 1618-1626
  • DOI: 10.1074/jbc.m110.198416
  • Peer Reviewed
• [Journal Article] Sodium-dependent phosphate cotransporters : Lessons from gene knock out mutation studies (2011)
  • Author(s): Miyamoto K, et al
  • Journal Title: J Pharm Sci Volume: 100 Issue: 9 Pages: 3719-3730
  • DOI: 10.1002/jps.22614
  • Peer Reviewed
• [Journal Article] Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo (2011)
  • Author(s): Liu Z, Segawa H, Aydin C, Reyes M, Erben RG, Weinstein LS, Chen M, Marshansky V, Fröhlich LF, Bastepe M
  • Journal Title: Endocrinology Volume: 152 Issue: 4 Pages: 1222-1233
  • DOI: 10.1210/en.2010-1034
  • Peer Reviewed
• [Journal Article] Hypophosphatemia in vitamin D receptor null mice : effect of rescue diet on the developmental changes in renal Na+ -dependent phosphate cotransporters (2011)
  • Author(s): Kaneko I, Segawa H, Furutani J, Kuwahara S, Aranami F, Hanabusa E, Tominaga R, Giral H, Caldas Y, Levi M, Kato S, Miyamoto K
  • Journal Title: Pflugers Arch Volume: 461 Issue: 1 Pages: 77-90
  • DOI: 10.1007/s00424-010-0888-z
  • Peer Reviewed
• [Presentation] リン代謝調節機序におけるNaPiトランスポーターの役割 (2014)
  • Author(s): 瀬川 博子、宮本 賢一
  • Organizer: 日本農芸化学会2014年度（平成26年度）大会
  • Place of Presentation: 明治大学生田キャンパス（東京都）
  • Invited
• [Presentation] Hepatectomy Hypophosphatemia : A Novel Phosphaturic Factor in the Liver Kidney Axis (2013)
  • Author(s): Nomura K, Tatsumi S, Miyagawa A, Shiozaki Y, Sasaki S, Segawa H, Miyamoto K
  • Organizer: American Society of Nephrology Annual Meeting
  • Place of Presentation: Georgia World Congress Center, Atlanta, GA, USA
  • Year and Date: 2013-11-08
• [Presentation] リンの吸収と排泄の生体内調節 (2013)
  • Author(s): 瀬川博子,向井朋,森絢香,佐々木祥平,宮本賢一
  • Organizer: 第56回日本腎臓学会学術総会
  • Place of Presentation: 東京国際フォーラム（東京都）
  • Invited
• [Presentation] Klothoによるリン代謝制御と老化 (2013)
  • Author(s): 瀬川博子,佐々木祥平,宮本賢一
  • Organizer: 第43回日本腎臓学会西部学術大会.
  • Place of Presentation: 松山全日空ホテル（愛媛県）
  • Invited
• [Presentation] リン利尿におけるKlothoの役割 (2013)
  • Author(s): 佐々木祥平、瀬川博子、 大西沙織、森絢香、向井朋、真鍋舞、日下祐里、木戸慎介、辰巳佐和子、宮本賢一
  • Organizer: 第56回日本腎臓学会学術総会
  • Place of Presentation: 東京国際フォーラム（東京都）
• [Presentation] 生体内リン代謝調節機構における唾液腺の関与 (2013)
  • Author(s): 生田かよ、 瀬川博子、向井朋、佐々木祥平、 森絢加、石川康子、上田乙也、堀場直、寺社下浩一、福島直、宮本賢一
  • Organizer: 第86回日本生化学会大会
  • Place of Presentation: パシフィコ横浜（神奈川県）
• [Presentation] Molecular mechanisms of cadmium (Cd) dependent fibroblast growth factor 23 secretion in bone (2012)
  • Author(s): Kido S, Fujiwara M, Nomura K, Sasaki S, Shiozaki Y, Segawa H, Tatsumi S, Miyamoto K
  • Organizer: American Society of Nephrology Annual Meeting
  • Place of Presentation: San Diego Convention Center, San Diego, CA, USA.
  • Year and Date: 2012-11-02
• [Presentation] Mechanisms of hyperphosphatemia in the osteocyte-abelated mice (2012)
  • Author(s): Tatsumi S, Kamatani T, Nomura K, Yoshimi A, Shiozaki Y, Sasaki S, Manabe M, Kido S, Segawa H, Miyamoto K
  • Organizer: American Society of Nephrology Annual Meeting
  • Place of Presentation: San Diego Convention Center, CA, USA.
  • Year and Date: 2012-11-02
• [Presentation] The Membrane Cytoskeletal Crosslinker Ezrin Is Essential for the Regulation of Phosphate Homeostasis in the Kidney (2012)
  • Author(s): Hatano R, Segawa H, Tamura A, Miyamoto K, Tsukita S, Asano S
  • Organizer: American Society of Nephrology Annual Meeting
  • Place of Presentation: San Diego Convention Center, San Diego, CA, USA.
  • Year and Date: 2012-11-01
• [Presentation] Clinical consequences of gene mutations involved in renal phosphate transport (2012)
  • Author(s): Miyamoto K, Ohnishi S, Shiozaki Y, Segawa H, Tatsumi S
  • Organizer: International Symposium on Epithelial Barrier and Transport
  • Place of Presentation: Ritsumeikan University. Kusatsu, Shiga, Japan.
  • Year and Date: 2012-09-16
• [Presentation] CKDにおけるリン代謝異常:吸収と排泄における問題点 (2012)
  • Author(s): 瀬川博子、宮本賢一
  • Organizer: 第30回日本骨代謝学会学術集会
  • Place of Presentation: 京王プラザホテル、東京都
  • Year and Date: 2012-07-19
• [Presentation] Dietary inorganic phosphorus and intestinal peptide absorption (2012)
  • Author(s): Segawa H, Furutani J, Miyamoto K
  • Organizer: XVI International Congress on Nutrition and Metabolism in Renal Disease
  • Place of Presentation: Hilton Hawaian Village, Hawaii. USA
  • Year and Date: 2012-06-29
• [Presentation] The role of salivary glands in phosphate homeostasis (2012)
  • Author(s): Mukai T, Segawa H, Sasaki S, Ohnishi S, Ishikawa Y, Horiba N, Ueda O, Jishage K, Fukushima N, Kido S, Miyamoto K
  • Organizer: XVI International Congress on Nutrition and Metabolism in Renal Disease
  • Place of Presentation: Hilton Hawaian Village, Hawaii, USA
  • Year and Date: 2012-06-29
• [Presentation] Muscle atrophy in patients with CKD results from FGF23/Klotho-mediated suppression of Insulin/IGF-I signaling (2012)
  • Author(s): Kido S, Hashimoto Y, Segawa H, Tatsumi S, Miyamoto K
  • Organizer: XVI International Congress on Nutrition and Metabolism in Renal Disease
  • Place of Presentation: Hilton Hawaian Village, Hawaii, USA.
  • Year and Date: 2012-06-27
• [Presentation] 生体内リン代謝調節機構における唾液腺の関与 (2012)
  • Author(s): 向井朋、瀬川博子、宮本賢一
  • Organizer: 第66回日本栄養・食糧学会大会
  • Place of Presentation: 東北大学、宮城県
  • Year and Date: 2012-05-19
• [Presentation] カドミウム汚染によるリン代謝異常;骨軟化症発症機序およびバイオマーカーの探索 (2012)
  • Author(s): 藤原真里奈
  • Organizer: 第244回徳島医学会学術集会
  • Place of Presentation: 徳島大学(徳島県)
  • Year and Date: 2012-02-12
• [Presentation] ナトリウム依存性リン酸トランスポーターNpt2bの新たな生理機能の解明 (2012)
  • Author(s): 向井朋、瀬川博子、宮本賢一
  • Organizer: 病態栄養学会
  • Place of Presentation: 国際会議場、京都府
  • Year and Date: 2012-01-14
• [Presentation] 骨細胞とリン代謝 (2012)
  • Author(s): 釜谷達哉
  • Organizer: 第15回日本病態栄養学会年次学術集会
  • Place of Presentation: 国立京都国際会館(京都府)
  • Year and Date: 2012-01-14
• [Presentation] カドミウム汚染によるリン代謝異常:骨軟化症発症機序の検討 (2012)
  • Author(s): 藤原真理奈
  • Organizer: 第15回日本病態栄養学会年次学術集会
  • Place of Presentation: 国立京都国際会館(京都府)
  • Year and Date: 2012-01-14
• [Presentation] ナトリウム依存性リン酸トランスポーターNpt2bの新たな生理機能の解析 (2012)
  • Author(s): 向井朋
  • Organizer: 第15回日本病態栄養学会年次学術集会
  • Place of Presentation: 国立京都国際会館(京都府)
  • Year and Date: 2012-01-14
• [Presentation] 糖尿病に併存する腎障害・骨障害の発症及び進展におけるFGF23の関与 (2012)
  • Author(s): 木戸慎介
  • Organizer: 第15回日本病態栄養学会年次学術集会
  • Place of Presentation: 国立京都国際会館(京都府)
  • Year and Date: 2012-01-14
• [Presentation] リン代謝における腸管の役割 (2012)
  • Author(s): 宮本賢一
  • Organizer: 第15回日本病態栄養学会年次学術集会
  • Place of Presentation: 国立京都国際会館(京都府)
  • Year and Date: 2012-01-14
• [Presentation] The role of salivary glands in phosphate homeostasis. (2012)
  • Author(s): Mukai T. et al.
  • Organizer: International Congress on Nutrition and Metabolism in Renal Disease
  • Place of Presentation: Hilton, Honolulu, Hawai, USA
• [Presentation] Dietary inorganic phosphorus and intestinal peptide absorption. (2012)
  • Author(s): Segawa H. et al.
  • Organizer: International Congress on Nutrition and Metabolism in Renal Disease
  • Place of Presentation: Hilton, Honolulu, Hawai, USA
• [Presentation] The membrane cytoskeletal crosslinker ezrin is essential for the regulation of phosphate homeostasis in the kidney (2012)
  • Author(s): Hatano R et al.
  • Organizer: Americal Society Nephrology, Kidney Week.
  • Place of Presentation: San Diego Convention Center, San Diego, CA, USA
• [Presentation] 生体内リン代謝調節機構における唾液腺の関与 (2012)
  • Author(s): 向井 朋ら
  • Organizer: 第66回日本栄養・食糧学会大会
  • Place of Presentation: 東北大学（宮城）
• [Presentation] リン代謝調節機構 (2012)
  • Author(s): 瀬川 博子
  • Organizer: 第55回日本腎臓学会学術総会
  • Place of Presentation: パシフィコ横浜（神奈川）
  • Invited
• [Presentation] CKDにおけるリン代謝異常：吸収と排泄における問題点 (2012)
  • Author(s): 瀬川博子
  • Organizer: 第30回日本骨代謝学会学術集会
  • Place of Presentation: 京王プラザホテル（東京）
  • Invited
• [Presentation] 糖尿病合併症発症におけるFGF23/Klothoの関与 (2011)
  • Author(s): 橋本由衣
  • Organizer: 第44回日本栄養食糧学会中四国支部大会
  • Place of Presentation: 岡山県立大学(岡山県)
  • Year and Date: 2011-11-13
• [Presentation] Post-Hepatectomy Hypophosphatemia in Rats (2011)
  • Author(s): Kengo Nomura
  • Organizer: American Society of Nephrology
  • Place of Presentation: Pennsylvania Convention Center (Philadelphia)
  • Year and Date: 2011-11-12
• [Presentation] Post-Hepatectomy Hypophosphatemia in Rats (2011)
  • Author(s): Nomura K, Tatsumi S, Shiozaki Y, Yamaguchi S, Kamatani T, Segawa H, Kido S, Miyamoto K
  • Organizer: The American Society of Nephrology Annual Meeting
  • Place of Presentation: Pennsylvania Convention Center, PA, USA
  • Year and Date: 2011-11-11
• [Presentation] Role of Sodium-Dependent Phosphate (Pi) Transporter (Npt2b) on Salivary Pi Secretion (2011)
  • Author(s): Segawa H, Mukai T, Ohnishi S, Sasaki S, Ohi A, Kuwahara S, Kido S, Tatsumi S, Ishikawa Y, Ueda O, Horiba N, Jishage K, Fukushima N, Miyamoto K
  • Organizer: The American Society of Nephrology Annual Meeting
  • Place of Presentation: Pennsylvania Convention Center, PA, USA
  • Year and Date: 2011-11-11
• [Presentation] Molecular Consequences of the SLC34A3 Mutations of Hereditary Hypophosphatemic Rickets with Hypercalciuria (HHRH) (2011)
  • Author(s): Ohi A, Haito-Sugino S, Ito M, Shiozaki Y, Nomura K, Kusaka Y, Sasaki S, Ohnishi S, Yamaguchi S, Kiso S, Tatsumi S, Segawa H, Miyamoto K
  • Organizer: The American Society of Nephrology Annual Meeting
  • Place of Presentation: Pennsylvania Convention Center, PA, USA
  • Year and Date: 2011-11-11
• [Presentation] Role of Sodium-Dependent Phosphate (Pi) Transporter (Npt2b) on Salivary Pi Sed (2011)
  • Author(s): Hiroko Segawa
  • Organizer: American Society of Nephrology
  • Place of Presentation: Pennsylvania Convention Center (Philadelphia)
  • Year and Date: 2011-11-11
• [Presentation] Molecular Consequences of the SLC34A3 Mutations of Hereditary Hypophosphatemic Rickets with Hypercalciuria(HHRH) (2011)
  • Author(s): Akiko Ohi
  • Organizer: American Society of Nephrology
  • Place of Presentation: Pennsylvania Convention Center (Philadelphia)
  • Year and Date: 2011-11-10
• [Presentation] ナトリウム依存性リン酸トランスポーターNpt2bの新たな生理機能の解明 (2011)
  • Author(s): 向井朋、瀬川博子、宮本賢一
  • Organizer: 第41回日本腎臓学会東西学術集会西部大会
  • Place of Presentation: あわぎんホール、徳島
  • Year and Date: 2011-10-01
• [Presentation] Hereaitary hypophosphatemic rickets with hypercalciuria (HHRH)やFanconi's syndromeにおける低リン血症の分子機構解明 (2011)
  • Author(s): 大西沙織
  • Organizer: 第41回日本腎臓学会西部学術大会
  • Place of Presentation: あわぎんホール(徳島県)
  • Year and Date: 2011-09-30
• [Presentation] ナトリウム依存性リン酸トランスポーターNpt2bの新たな生理機能の解明 (2011)
  • Author(s): 向井朋
  • Organizer: 第41回日本腎臓学会西部学術大会
  • Place of Presentation: あわぎんホール(徳島県)
  • Year and Date: 2011-09-30
• [Presentation] Phospholipase C signaling through the PTH/PTHrP receptor is required for serum phosphate homeostasis but not for serum 1,25(OH)2D3 (2011)
  • Author(s): Jun Guo
  • Organizer: American Society for Bone and Mineral Research
  • Place of Presentation: San Diego (California)
  • Year and Date: 2011-09-16
• [Presentation] レチノイン酸はI I b型リン酸トランスポーターNpt2b発現を抑制し小腸リン吸収を低下させる (2011)
  • Author(s): 山本浩範
  • Organizer: 第29回日本骨代謝学会学術集会
  • Place of Presentation: 大阪国際会議場(大阪府)
  • Year and Date: 2011-07-30
• [Presentation] 敗血症時におけるリン代謝異常の分子メカニズムの解析 (2011)
  • Author(s): 山本浩範
  • Organizer: 第29回日本骨代謝学会学術集会
  • Place of Presentation: 大阪国際会議場(大阪府)
  • Year and Date: 2011-07-28
• [Presentation] イタイイタイ病に見られる骨障害の発症・進展におけるFGF23の関与 (2011)
  • Author(s): 木戸慎介
  • Organizer: 第29回日本骨代謝学会学術集会
  • Place of Presentation: 大阪国際会議場(大阪府)
  • Year and Date: 2011-07-28
• [Presentation] リン代謝調節機構up to date (2011)
  • Author(s): 瀬川博子
  • Organizer: 第56回日本透析医学会学術集会・総会
  • Place of Presentation: パシフィコ横浜(神奈川県)(招待講演)
  • Year and Date: 2011-06-17
• [Presentation] リン酸トランスポーターと慢性腎臓病 (2011)
  • Author(s): 瀬川博子
  • Organizer: 第54回日本腎臓学会学術総会
  • Place of Presentation: パシフィコ横浜、神奈川県
  • Year and Date: 2011-06-15
• [Presentation] レチノイン酸受容体RAR/RXRを介したナトリウム依存性リン酸輸送担体遺伝子の発現調節機構 (2011)
  • Author(s): 山本浩範
  • Organizer: 第65回日本栄養・食糧学会大会
  • Place of Presentation: お茶の水女子大学(東京都)
  • Year and Date: 2011-05-15
• [Presentation] リン代謝におけるカルシウム受容体の役割 (2011)
  • Author(s): 辰巳佐和子
  • Organizer: 第65回日本栄養・食糧学会大会
  • Place of Presentation: お茶の水女子大学(東京都)
  • Year and Date: 2011-05-15
• [Presentation] イタイイタイ病に見られる骨障害の発症・進展におけるFGF23の関与 (2011)
  • Author(s): 木戸慎介
  • Organizer: 第65回日本栄養・食糧学会大会
  • Place of Presentation: お茶の水女子大学(東京都)
  • Year and Date: 2011-05-15
• [Presentation] 慢性腎臓病における食事リンによる腸管ペプチドトランスポーター調節 (2011)
  • Author(s): 瀬川博子
  • Organizer: 第65回日本栄養・食糧学会大会
  • Place of Presentation: お茶の水女子大学(東京都)
  • Year and Date: 2011-05-15
• [Book] リンの吸収と排泄, CKD-MBDハンドブック2nd Edition (2013)
  • Author(s): 瀬川博子、宮本賢一
  • Total Pages: 325
  • Publisher: 日本メディカルセンター
• [Book] リン輸送と疾患. 腎と骨代謝 (2013)
  • Author(s): 瀬川博子、大西沙織、塩崎雄治、佐々木祥平、宮本賢一
  • Total Pages: 250
  • Publisher: 日本メディカルセンター