Analysis of the physiology of mitochondrial morphology control by MARCH-V
| Project/Area Number |
23700517
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Laboratory animal science
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| Research Institution | Gunma University (2012)
The Institute of Physical and Chemical Research (2011) |
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Principal Investigator |
GOTO Eiji 群馬大学, 生体調節研究所, 助教 (40435649)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ミトコンドリア / ユビキチン / 胎生致死 / E3ユビキチンリガーゼ |
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| Research Abstract |
In this study, by using the MARCH-V knockout mice, I demonstrated that mice lacking MARCH-V die after embryonic day 10.5. Moreover, histological studies revealed that loss of MARCH-V led to proliferative abnormality of neuroepithelial cells.
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Report
(3 results)
Research Products
(5 results)
