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Establishment of new technologies related to environmental improvement of bone interface between the inorganic material or bone tissue

Research Project

Project/Area Number 23700528
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biological material science
Research InstitutionNiigata University

Principal Investigator

MATSUDA Junpei  新潟大学, 医歯(薬)学総合研究科, 研究員 (00535271)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywordsバイオエンジニアリング / 骨 / インプラント / 医用生体工学 / 再生医療 / オステオインテグレーション / スキャフォールド
Research Abstract

In order to improve the bone inductivity of bone and implant, we developed free-shaped bubble like scaffold. In this study, it was possible to evaluate the performance and establishment of a new scaffold technology to create and present new options in the regenerated tissue culture. As a result of evaluating the relationship between the mechanical stimulation conductive, new scaffold showed mechanical response higher than general. Morphological features of trabecular bone-like tissue was dependent on the bubble diameter. For response to mechanical stress of a new scaffold, trabecular structure was maintained for shear stimulus of 0.5%. In addition, I was confirmed that the trabecular bone-like tissue is transmitting mechanical stress.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (8 results)

All 2013 2012 2011

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (5 results)

  • [Journal Article] 全身振動刺激(Whole-Body Vibration)がマウスの不動性骨組織に与える影響2013

    • Author(s)
      松田純平 ,遠藤直人
    • Journal Title

      Osteoporosis Japan

      Volume: Vol.21(2) Pages: 344-351

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 骨構造からみた廃用性骨粗鬆症に対する全身振動刺激の影響2013

    • Author(s)
      松田純平
    • Journal Title

      Bio Clinica

      Volume: 28(10) Pages: 972-975

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 全身振動(Whole-body vibration)がマウスの骨組織に与える影響2013

    • Author(s)
      松田純平、遠藤直人
    • Journal Title

      Osteoporosis japan

      Volume: Vol.21 No.2 Pages: 344-351

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] 関節安定性不全膝に対する副甲状腺ホルモン投与が股関節の骨形態に及ぼす影響2012

    • Author(s)
      松田純平,遠藤直人
    • Organizer
      第39回日本股関節学会学術集会
    • Place of Presentation
      新潟
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] 全身振動刺激(Whole-Body Vibration)がマウスの不動性骨組織に与える影響2012

    • Author(s)
      松田純平 ,遠藤直人
    • Organizer
      第14回日本骨粗鬆症学会
    • Place of Presentation
      新潟
    • Related Report
      2013 Final Research Report
  • [Presentation] 全身振動刺激(Whole-Body Vibration)がマウスの不動性骨組織に与える影響2012

    • Author(s)
      松田純平、遠藤直人
    • Organizer
      第14回日本骨粗鬆症学会
    • Place of Presentation
      新潟
    • Related Report
      2012 Research-status Report
  • [Presentation] 変形性関節症による軟骨下骨および軟骨下骨フレートの形態的影響2011

    • Author(s)
      松田純平,原利昭,遠藤直人
    • Organizer
      第23回運動器リハビリテーション学会
    • Place of Presentation
      新潟
    • Related Report
      2013 Final Research Report
  • [Presentation] 変形性関節症による軟骨下骨および軟骨下骨プレートの形態的影響2011

    • Author(s)
      松田純平,原利昭,遠藤直人
    • Organizer
      第23回運動器リハビリテーション学会
    • Place of Presentation
      新潟コンベンションセンター(新潟)
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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