Project/Area Number |
23700528
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Biomedical engineering/Biological material science
|
Research Institution | Niigata University |
Principal Investigator |
MATSUDA Junpei 新潟大学, 医歯(薬)学総合研究科, 研究員 (00535271)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
|
Keywords | バイオエンジニアリング / 骨 / インプラント / 医用生体工学 / 再生医療 / オステオインテグレーション / スキャフォールド |
Research Abstract |
In order to improve the bone inductivity of bone and implant, we developed free-shaped bubble like scaffold. In this study, it was possible to evaluate the performance and establishment of a new scaffold technology to create and present new options in the regenerated tissue culture. As a result of evaluating the relationship between the mechanical stimulation conductive, new scaffold showed mechanical response higher than general. Morphological features of trabecular bone-like tissue was dependent on the bubble diameter. For response to mechanical stress of a new scaffold, trabecular structure was maintained for shear stimulus of 0.5%. In addition, I was confirmed that the trabecular bone-like tissue is transmitting mechanical stress.
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