• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Synthetic Study on Chlorosulfolipid toward elucidation of toxicity

Research Project

Project/Area Number 23710245
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Living organism molecular science
Research InstitutionHokkaido University

Principal Investigator

UMEZAWA Taiki  北海道大学, 大学院・地球環境科学研究院, 准教授 (20503618)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsクロロスルフォリピッド / 全合成 / 有機合成化学 / 含塩素化合物
Research Abstract

According to the plan, the synthesis of two fragments for the chlorosulfolipid and a coupling reaction conditions with the fragments were examined. As a results of the examinations, the efficient synthesis of one fragment was developed, and a new synthetic method for the synthesis of another fragment was established. The method is used for the synthesis of, -unsaturated ketone with aldehyde, trimethylsilylmethyl phosphonate, and acyl fluoride in one step, and published from a journal, Organic Letters. Synthesis of chlorosulfolipid is currently underway using the method.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (6 results)

All 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (5 results)

  • [Journal Article] Novel One-pot Three-component Coupling Reaction with Acyl Fluoride, Trimethylsilylmethylphosphonate, and Aldehyde through Horner-Wadsworth-Emmons Reaction2012

    • Author(s)
      梅澤大樹
    • Journal Title

      Organic Letters

      Volume: 14 Issue: 16 Pages: 4206-4209

    • DOI

      10.1021/ol301879a

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Presentation] Mytilipin C の全合成研究2013

    • Author(s)
      梅澤大樹、清野智也、松田冬彦
    • Organizer
      第93 日本化学会春季年会
    • Place of Presentation
      立命館大学(草津市)
    • Year and Date
      2013-03-25
    • Related Report
      2012 Final Research Report
  • [Presentation] Mytilipin Cの全合成研究2013

    • Author(s)
      梅澤大樹
    • Organizer
      第93日本化学会春季年会
    • Place of Presentation
      立命館大学(草津市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] アルデヒド酸フッ化物、トリメチルシリルメチルホスホネートの3成分カップリング2012

    • Author(s)
      清野智也、梅澤大樹、松田冬彦
    • Organizer
      日本化学会北海道支部 2012 年 夏季研究発表会
    • Place of Presentation
      旭川高専(旭川市)
    • Year and Date
      2012-08-04
    • Related Report
      2012 Final Research Report
  • [Presentation] アルデヒド、酸フッ化物、トリメチルシリルメチルホスホネートの3成分カップリング反応、2012

    • Author(s)
      梅澤大樹、清野智也、松田冬彦
    • Organizer
      第92 日本化学会春季年会
    • Place of Presentation
      慶應義塾大学 (横浜市)
    • Year and Date
      2012-03-28
    • Related Report
      2012 Final Research Report
  • [Presentation] アルデヒド、酸フッ化物、トリメチルシリルメチルホスホネートの3成分カップリング2012

    • Author(s)
      清野智也
    • Organizer
      日本化学会北海道支部2012年 夏季研究発表会
    • Place of Presentation
      旭川高専(旭川市)
    • Related Report
      2012 Annual Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi