Multiple approach to the exploration of neural substrates for interval timing in rats
Project/Area Number |
23730712
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Experimental psychology
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Research Institution | Doshisha University |
Principal Investigator |
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Project Period (FY) |
2011-04-28 – 2015-03-31
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Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | 時間評価 / インターバルタイミング / 背側線条体 / SBFモデル / Striatal beat frequency / NMDA / グルタミン酸受容体 / アセチルコリン受容体 / 情動 |
Outline of Final Research Achievements |
We explored the role of the dorsal striatum in interval timing ranging from seconds to minutes. Intra dorsal striatum injection of an NMDA receptor antagonist impaired the acquisition of the memory for temporal duration. Moreover, c-Fos protein expression was enhanced during temporal memory formation in the dorsal striatum. Taken together, these findings suggest that the dorsal striatum plays an important role in the formation of memory for temporal duration.
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Report
(5 results)
Research Products
(19 results)
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[Presentation] Effect of NMDA receptor blockade on acquisition of memory for duration in rats.2012
Author(s)
Oka, M., Ishino, S., Yanai, S., Okaichi, H., Hata, T.
Organizer
42th Society for Neuroscience
Place of Presentation
New Orleans, USA
Related Report
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