Development of new chiral organobase c atalyst and app lication tothe direct asymmetric aldol reaction
| Project/Area Number |
23750046
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Organic chemistry
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| Research Institution | University of Hyogo |
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Principal Investigator |
MISAKI Tomonori 兵庫県立大学, 物質理学研究科, 助教 (00411786)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 合成有機化学 / 不斉有機分子触媒 / 不斉合成 / 不斉反応 / 不斉有機触媒 |
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| Research Abstract |
The direct vinylogousaldol reaction of γ-CF3substituted azlactone was smoothly proceeded with high syn/anti selectivity (97:3~99:1) and moderate enantioselectivity (up to 39% ee) by using our original chiral guanidine catalyst.
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Report
(3 results)
Research Products
(18 results)
