| Project/Area Number |
23770087
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biodiversity/Systematics
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 発生過程安定性 / 量的遺伝学 / 形態測定学 / 進化可能性 / 遺伝変異緩衝機構 / 環境変異環境機構 / ゆらぎ非対称性 |
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| Research Abstract |
A conceptual machinery called an evolutionary capacitor buffers genetic and environmental perturbations and keeps genetic variation cryptic, accumulating mutations in a population. In the current study, I used Drosophila melanogaster as a study material, and searched for genomic regions that regulated natural genetic variation in wing morphology using isogenic deficiency strains. As a result, multiple genomic regions were shown to affect quantitative genetic variation and significantly increased broad-sense heritability of wing shape. In addition, several genomic deletions revealed qualitative cryptic genetic variation in wing morphology such as extra wing compartment, lack of wing vein etc. These results indicate the existence of multiple capacitors for natural genetic variation, and the genomic regions with effect on natural genetic variation may encompass candidate genes for evolutionary capacitors.
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