Function and application of a new glycated peptide withanti-biofilm effect
Project/Area Number |
23780137
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Food science
|
Research Institution | Kyushu University |
Principal Investigator |
NOMA Seiji 九州大学, 大学院・農学研究院, 助教 (40392071)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
|
Keywords | 糖付加 / ペプチド / バイオフィルム / メイラード反応 |
Research Abstract |
LK(Glc)G has shown to have an inhibitory effect on biofilm formation in Staphylococcus aureuscells. LK(Glc)G decreased cell proliferation and appeared to alter the behavior of cell adhesion. The inhibitory effect was disappeared by alkylation of ε-amino residue instead of the glycation with sugars, and was weakened by depletion of L or G.
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Report
(3 results)
Research Products
(4 results)