Elucidation of chemotherapy related factor of the preoperativechemotherapy for advanced gastric cancer and establishment of curative effect prediction system

Research Project

Project/Area Number	23790416
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Human pathology
Research Institution	Kitasato University
Principal Investigator	ICHINOE Masaaki 北里大学, 医学部, 講師 (80365163)
Project Period (FY)	2011 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000) Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000) Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords	進行胃癌 / 化学療法 / 治療効果 / 胃癌
Research Abstract	Clinicopathological feature of chemotherapy effective group showed the frequency of lymph node metastasis and the frequency of poorly differentiated cancer were low tendencies. In chemotherapy effective group, there was significant higher LAT1 score than in chemotherapy resistance group. Further, there was significant low Ki-67LI than in chemotherapy group in the surgical specimen. There was the possibility that LAT1 expression at biopsy could become a useful marker in predicting curative effect was suggested at present.

Report

(3 results)