Function analysis of SGSM family and RAB11 which associate with the vesicular transportation of prion protein
| Project/Area Number |
23790418
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Human pathology
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| Research Institution | Keio University |
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Principal Investigator |
YANG Hao 慶應義塾大学, 医学部, 特任助 (10464992)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 脳・神経 / プリオンタンパク / SGSMファミリータンパク / 神経 / RABファミリータンパク |
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| Research Abstract |
SGSM family proteins interact with RAB11 which regulates the vesicular transportation of prion protein, and might participate in the pathogenesis of hereditary prion disease. The association between SGSM family and RAB family was analyzed by molecular bio
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Report
(3 results)
Research Products
(3 results)
