diagnostics development of unstableatherosclerosis based on new technology
| Project/Area Number |
23790600
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Applied pharmacology
|
|---|
| Research Institution | Okayama University |
|---|
Principal Investigator |
OGAWA Hiroko 岡山大学, 岡山大学病院, 助教 (70423283)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | イメージング / 動脈硬化 / リポソーム |
|---|
| Research Abstract |
Detection of vulnerable plaque is a promising strategy for atherosclerosis imaging. Vulnerable plaque is characterized by the infiltration of inflammatory cells. SLX-Lipo-statin attenuated the inflammation of atherosclerotic lesions in vivo, which was monitored non-invasively. We demonstrated that E-selectin-targeted liposomes can be a powerful tool for the detection of and the treatment for atheromatous plaques with the advantage of non-invasive and repeatable assessment.
|
Report
(3 results)
Research Products
(18 results)
-
[Journal Article] Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis2012
Author(s)
Obika M, Ogawa H, Takahashi K, Li J, Hatipoglu OF, Cilek MZ, Miyoshi T,Inagaki J, Ohtsuki T, Kusachi S, Ninomiya Y, Hirohata S
-
Journal Title
Cancer Sci
Volume: 103(10)
Pages: 1889-97
NAID
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
