Experimental study for "non-exposed endoscopic wall-inversion surgery" as a new method of minimally-invasive surgery for gastric tumors

• Project/Area Number: 23790770
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Gastroenterology
• Research Institution: Keio University
• Principal Investigator: GOTO Osamu 慶應義塾大学, 医学部, 特任助 (00589658)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 胃癌 / 胃粘膜下腫瘍 / 低侵襲 / 内視鏡 / 腹腔鏡 / 手術 / 局所切除 / 内視鏡的粘膜縫合 / センチネルリンパ節

Research Abstract

The study was aimed to demonstrate feasibility and safety of non-exposed endoscopic wall-inversion surgery (NEWS)as a new method of minimally-invasive surgery for gastric tumors in porcine models. We elucidate that NEWS was feasible in ex vivo study using

Research Products

• [Journal Article] Novel technique for full-thickness resection of gastric malignancy: Feasibility of non-exposed endoscopic wall-inversion surgery (NEWS) in porcine models (2013)
  • Author(s): Mitsui T, Goto O, et al.
  • Journal Title: Surgical laparoscopy, endoscopy and percutaneous techniques Volume: 未定
  • Peer Reviewed
• [Journal Article] NEWS (non-exposed endoscopic wall-inversion surgery). (2012)
  • Author(s): 後藤修ら
  • Journal Title: 臨牀消化器内科 Volume: 27 Pages: 483-6
• [Journal Article] NEWS(non-exposed endoscopic wall-inversion surgery) (2012)
  • Author(s): 後藤修、他
  • Journal Title: 臨牀消化器内科 Volume: 27 Pages: 483-486
• [Journal Article] 消化器内視鏡の診断と外科治療への応用胃. (2011)
  • Author(s): 和田郁雄、三ツ井崇司、後藤修ら
  • Journal Title: 臨床外科 Volume: 66 Pages: 1602-8
• [Journal Article] 消化器内視鏡の診断と外科治療への応用 胃 (2011)
  • Author(s): 和田郁雄、三ツ井崇司、後藤修、他
  • Journal Title: 臨床外科 Volume: 66 Pages: 1602-1608
• [Journal Article] Novel technique for full-thickness resection of gastric malignancy: Feasibility of non-exposed endoscopic wall-inversion surgery (NEWS) in porcine models
  • Author(s): Mitsui T, Goto O (corresponding author), (他8 名).
  • Journal Title: Surg Laparosc Endosc Percutan Tech Volume: (in press)
  • Peer Reviewed
• [Presentation] Feasibility of endoscopic hand-sewn suturing as a new method of closure for an iatrogenic gastric mucosal defect in porcine models (2013)
  • Author(s): Goto O, et al
  • Organizer: Digestive Disease Week 2012
  • Place of Presentation: Orlando, FL, USA
  • Year and Date: 2013-05-18
• [Presentation] 胃粘膜下腫瘍に対する非穿孔式内視鏡的胃壁内反切除術(NEWS)～安全性の確認と当院での臨床導入を目指した慢性実験 (2013)
  • Author(s): 後藤修ら
  • Organizer: 第85回日本消化器内視鏡学会総会
  • Place of Presentation: 京都
  • Year and Date: 2013-05-11
• [Presentation] 胃ESD後出血と遅発性穿孔の予防を目指した内視鏡的粘膜連続縫合法に関する基礎実験 (2013)
  • Author(s): 後藤修
  • Organizer: 第85回日本消化器内視鏡学会総会
  • Place of Presentation: 京都
  • Year and Date: 2013-05-10
• [Presentation] 内視鏡的粘膜連続縫合法の有用性に関する比較実験 (2013)
  • Author(s): 後藤修ら
  • Organizer: 第9回日本消化管学会総会学術集会
  • Place of Presentation: 東京
  • Year and Date: 2013-01-25
• [Presentation] Feasibility of endoscopic hand-sewn suturing as a new method of closure for an iatrogenic gastric mucosal defect in porcine models (2013)
  • Author(s): Goto O, et al.
  • Organizer: Digestive Disease Week 2012
  • Place of Presentation: Orlando, FL, USA
• [Presentation] 非穿孔式胃壁内反切除術(Non-exposed endoscopic wall-inversion surgery; NEWS)の臨床報告 (2012)
  • Author(s): 三ツ井崇司、新美惠子、後藤修ら
  • Organizer: 第25回日本内視鏡外科学会
  • Place of Presentation: 横浜
  • Year and Date: 2012-12-06
• [Presentation] 早期胃癌に対する非穿孔式内視鏡的胃壁内反切除術(NEWS)+腹腔鏡下センチネルリンパ節生検 (2012)
  • Author(s): 竹内裕也、後藤修ら
  • Organizer: 第25回日本内視鏡外科学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2012-12-06
• [Presentation] New method of endoscopic closure for an iatrogenic mucosal defect: an ex vivo comparative study of endoscopic continuous suturing. (2012)
  • Author(s): Goto O, et al.
  • Organizer: Asian Pacific Digestive Week 2012
  • Place of Presentation: Bangkok, Thailand.
  • Year and Date: 2012-12-05
• [Presentation] 非穿孔式内視鏡的胃壁内反切除術(Non-exposed endoscopic wall- inversion surgery;NEWS)の臨床導入～ブタ切除胃による実験からHuman caseまでの報告 (2012)
  • Author(s): 三ツ井崇司、新美惠子、後藤修ら
  • Organizer: 第74回日本臨床外科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2012-11-29
• [Presentation] Non-exposed endoscopic wall-inversion surgery (NEWS) as a new full-thickness resection method of the stomach: an in vivo porcine study (2012)
  • Author(s): Goto O, et al
  • Organizer: United European Gastroenterology Week 2012
  • Place of Presentation: Amsterdam, The Netherlands
  • Year and Date: 2012-10-16
• [Presentation] Novel technique for full-thickness resection in a survival porcine model. Non-exposed endoscopic wall- inversion surgery (NEWS). (2012)
  • Author(s): Mitsui T, Goto O, et al.
  • Organizer: The 20th International Congress of the European Association for Endoscopic Surgery
  • Place of Presentation: Brussels, Belgium
  • Year and Date: 2012-06-20
• [Presentation] Non-exposed endoscopic wall-inversion surgery (NEWS) の考案から臨床導入まで (2012)
  • Author(s): 後藤修ら
  • Organizer: 第83回日本消化器内視鏡学会総会
  • Place of Presentation: 東京
  • Year and Date: 2012-05-14
• [Presentation] NEWS (Non-exposed endoscopic wall- inversion surgery) の臨床導入に向けて～生体ブタを用いた生存実験による安全性の検討 (2012)
  • Author(s): 三ツ井崇司、後藤修ら
  • Organizer: 第112回日本外科学会定期学術集会
  • Place of Presentation: 幕張
  • Year and Date: 2012-04-12
• [Presentation] Novel technique for full-thickness resection in a survival porcine model. Non-exposed endoscopic wall-inversion surgery (NEWS) (2012)
  • Author(s): Mitsui T, Goto O, et al.
  • Organizer: The 20th International Congress of the European Association for Endoscopic Surgery
  • Place of Presentation: Brussels, Belgium
• [Presentation] New method of endoscopic closure for an iatrogenic mucosal defect: an ex vivo comparative study of endoscopic continuous suturing (2012)
  • Author(s): Goto O, et al.
  • Organizer: Asian Pacific Digestive Week 2012
  • Place of Presentation: Bangkok, Thailand
• [Presentation] NEWS(Non-exposed endoscopic wall-inversion surgery)の臨床導入に向けて 生体ブタを用いた生存実験による安全性の検討 (2012)
  • Author(s): 三ツ井崇司、後藤修ら
  • Organizer: 第112回日本外科学会定期学術集会
  • Place of Presentation: 幕張
• [Presentation] 非穿孔式内視鏡的胃壁内反切除術（Non-exposed endoscopic wall-inversion surgery；NEWS）の臨床導入～ブタ切除胃による実験からHuman caseまでの報告 (2012)
  • Author(s): 三ツ井崇司、新美惠子、後藤修ら
  • Organizer: 第74回日本臨床外科学会総会
  • Place of Presentation: 東京
• [Presentation] 非穿孔式胃壁内反切除術(Non-exposed endoscopic wall-inversion surgery; NEWS)の臨床報告 (2012)
  • Author(s): 三ツ井崇司、新美惠子、後藤修ら
  • Organizer: 第25回日本内視鏡外科学会総会
  • Place of Presentation: 横浜
• [Presentation] 非穿孔式内視鏡的胃壁内反切除術(NEWS)の確立へ向けた内視鏡的粘膜連続縫合法の検討 (2012)
  • Author(s): 後藤修ら
  • Organizer: 第95回日本消化器内視鏡学会関東支部会
  • Place of Presentation: 東京
• [Presentation] 早期胃癌に対する非穿孔式内視鏡的胃壁内反切除術(NEWS)+腹腔鏡下センチネルリンパ節生検の試み (2012)
  • Author(s): 竹内裕也、後藤修ら
  • Organizer: 第95回日本消化器内視鏡学会関東支部会
  • Place of Presentation: 東京
• [Presentation] 新しい胃全層切除術である非穿孔式内視鏡的胃壁内反切除術(NEWS)～縫合線方向による比較～ (2011)
  • Author(s): 三ツ井崇司、後藤修ら
  • Organizer: 第24回日本内視鏡外科学会総会
  • Place of Presentation: 大阪
  • Year and Date: 2011-12-08
• [Presentation] Feasibility of the advanced method of laparoscopic and endoscopic coop-erative surgery: a pilot study of non-exposed endoscopic wall-inversion surgery in a live porcine model. (2011)
  • Author(s): Goto O, et al
  • Organizer: 19th United European Gastroenterology Week
  • Place of Presentation: Stockholm, Sweden.
  • Year and Date: 2011-10-26
• [Presentation] 臨床導入を目指したNon-exposed endoscopic wall- inversion surgery (NEWS)の検証 (2011)
  • Author(s): 後藤修ら
  • Organizer: 第82回日本消化器内視鏡学会総会(JDDW2011)
  • Place of Presentation: 福岡
  • Year and Date: 2011-10-21
• [Presentation] 新しい胃全層切除術(非穿孔式内視鏡的胃壁内反切除術; NEWS)の実現可能性に関する検討. (2011)
  • Author(s): 三ツ井崇司、後藤修ら
  • Organizer: 第66回日本消化器外科学会総会
  • Place of Presentation: 名古屋
  • Year and Date: 2011-07-14
• [Presentation] Feasibility of novel technique for full-thickness resection in a porcine model:non-exposed endoscopic wall-inversion surgery (NEWS). (2011)
  • Author(s): Mitsui T, Goto O, et al
  • Organizer: 19th International Congress of the European Association for Endoscopic Surgery
  • Place of Presentation: Torino, Italy.
  • Year and Date: 2011-06-17
• [Presentation] 非穿孔式内視鏡的胃壁内反切除術に関する基礎実験 (2011)
  • Author(s): 後藤修ら.
  • Organizer: 第97回日本消化器病学会総会
  • Place of Presentation: 東京
  • Year and Date: 2011-05-13
• [Presentation] 新しい胃全層切除術である非穿孔式内視鏡的胃壁内反切除術（NEWS）～縫合線方向による比較～ (2011)
  • Author(s): 三ツ井崇司、後藤修、他
  • Organizer: 第24回日本内視鏡外科学会総会
  • Place of Presentation: 大阪国際会議場(大阪府)
• [Presentation] Feasibility of the advanced method of laparoscopic and endoscopic coop-erative surgery: a pilot study of non-exposed endoscopic wall-inversion surgery in a live porcine model (2011)
  • Author(s): Goto O, et al.
  • Organizer: 19th United European Gastroenterology Week
  • Place of Presentation: Stockholm (Sweden)
• [Presentation] 臨床導入を目指したNon-exposed endoscopic wall-inversion surgery(NEWS)の検証 (2011)
  • Author(s): 後藤修、他
  • Organizer: 第82回日本消化器内視鏡学会総会(JDDW2011)
  • Place of Presentation: 第82回日本消化器内視鏡学会総会(JDDW2011)2011年10月21日 マリンメッセ福岡(福岡県)
• [Presentation] 新しい胃全層切除術(非穿孔式内視鏡的胃壁内反切除術; NEWS)の実現可能性に関する検討 (2011)
  • Author(s): 三ツ井崇司、後藤修、他
  • Organizer: 第66回日本消化器外科学会総会
  • Place of Presentation: 名古屋国際会議場(愛知県)
• [Presentation] Feasibility of novel technique for full-thickness resection in a porcine model: non-exposed endoscopic wall-inversion surgery (NEWS). (2011)
  • Author(s): Mitsui T, Goto O, et al.
  • Organizer: 19th International Congress of the European Association for Endoscopic Surgery
  • Place of Presentation: Torino (Italy)
• [Presentation] 非穿孔式内視鏡的胃壁内反切除術に関する基礎実験 (2011)
  • Author(s): 後藤修、他
  • Organizer: 第97回日本消化器病学会総会
  • Place of Presentation: 京王プラザホテル(東京都)