| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
The applicant showed the role of inflammatory Ly6Chighmonocytes/macrophages in the development of abdominal aneurysm, and showed that nanoparticle-mediated delivery of a statin into circulation monocyte inhibited the recruitment of inflammatory monocytes and the development of abdominal aneurysm in an ApoE-deficient mouse model
The applicant showed the role of inflammatory Ly6Chighmonocytes/macrophages in the development of abdominal aneurysm, and showed that nanoparticle-mediated delivery of a statin into circulation monocyte inhibited the recruitment of inflammatory monocytes and the development of abdominal aneurysm in an ApoE-deficient mouse model.
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