A study regarding gene expressions of Sirt1 in human placentas of newborns with intrauterine growth restriction
Project/Area Number |
23791224
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Embryonic/Neonatal medicine
|
Research Institution | Kobe University |
Principal Investigator |
MORIOKA ICHIRO 神戸大学, 医学研究科, 特命教授 (80437467)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 子宮内胎児発育不全 / 遺伝子 / 血管内皮増殖因子 / レニン・アンジオテンシン系 / 多型 / 脂質 / 子宮内胎児発育遅延 / 遺伝子発現 / 低身長 / メタボリック症候群 |
Research Abstract |
A purpose of this study was to investigate expressions of Sirt1 gene in human placentas of newborns with intrauterine growth restriction (IUGR). No different expressions of Sirt1 gene were found between IUGR and appropriate-for-gestational age newborns. However, we found that the vascular endothelial growth factor and renin-angiotensin system gene polymorphisms are at risk for developing IUGR in Japanese newborns.
|
Report
(4 results)
Research Products
(30 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Extremely preterm severely small for gestational age newborns are at risk for motor developmental impairment at 3 years of age.2013
Author(s)
Morioka I, Mandai T, Nagasaka M, Koda T, Matsuo K, Yokota T, Morikawa S, Miwa A, Shibata A, Kitayama S, Iijima K.
Organizer
the Society for Pediatric Research Conference
Place of Presentation
Washington, DC, USA
Related Report
-
[Presentation] Incidence of short stature at 3 years of age in Japanese late-preterm infants.2013
Author(s)
Nagasaka M, Morioka I, Koda T, Matsuo K, Yokota T, Morikawa S, Miwa A, Shibata A, Ozaki A, Shirai C, Ijichi A, Iijima K.
Organizer
the Society for Pediatric Research Conference
Place of Presentation
Washington, DC, USA
Related Report
-
[Presentation] Association between renin-angiotensin systems gene polymorphisms and intrauterine growth restriction in a Japanese population.2013
Author(s)
Fujioka K, Morioka I, Nagasaka M, Koda T, Matsuo K, Yokota T, Morikawa S, Miwa A, Shibata A, Yamada H, Iijima K.
Organizer
the 9th Congress of Asian Society for Pediatric Research Conference
Place of Presentation
Sarawak, Malaysia
Related Report
-
-
-
-
-
[Presentation] Vascular endothelial growth factor genetic polymorphisms in newborns with intrauterine growth restriction.2012
Author(s)
Fujioka K, Morioka I, Yagi M, Koda T, Matsuo K, Yokota T, Morikawa S, Miwa A, Shibata A, Yokoyama N, Takeshima Y, Yamada H, Iijima K.
Organizer
the Society for Pediatric Research Conference
Place of Presentation
Boston, USA
Related Report
-
-
-
-