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Study of optimal method of probiotics supplementation for premature infants

Research Project

Project/Area Number 23791236
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Embryonic/Neonatal medicine
Research InstitutionJuntendo University

Principal Investigator

HISATA Ken  順天堂大学, 医学部, 准教授 (10420853)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
KeywordsProbiotics / 新生児 / 投与方法 / 浸透圧 / プロバイオティクス / 早産児 / 溶解方法
Research Abstract

Necrotizing enteritis is one of the severe complication of premature infants. Probiotic supplement reduces risk of necrotizing enterocolitis and mortality in preterm very low-birth-weight infants. Therefore, probiotics is supplied for premature infants in many neonatal intensive care units. However, those methods are various and different by each NICU. In this study, when dextrin was used as diluting agent, dissolution method with distilled water was thought to be optimal. In addition, we confirmed that probiotics have an influence on intestinal flora of infants after a discharge.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (3 results)

All 2012 2011 Other

All Journal Article (1 results) Presentation (2 results) (of which Invited: 1 results)

  • [Journal Article] 【新生児医療-up to date】プロバイオティクス2012

    • Author(s)
      久田研,清水俊明
    • Journal Title

      小児科診療

      Volume: Vol75, No9 Pages: 1578-1585

    • Related Report
      2013 Final Research Report
  • [Presentation] NICUにおけるプロバイオティクスの現状2011

    • Author(s)
      久田研
    • Organizer
      第114回小児科学会学術集会教育セミナー
    • Place of Presentation
      品川
    • Year and Date
      2011-08-14
    • Related Report
      2013 Final Research Report
  • [Presentation] プロバイオティクスの現状

    • Author(s)
      久田 研
    • Organizer
      新生児栄養フォーラム
    • Place of Presentation
      兵庫
    • Related Report
      2013 Annual Research Report
    • Invited

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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