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Basic research for the oscillations of the brain metabolism in neonates: analysis of the relationship between NIRS and EEG.

Research Project

Project/Area Number 23791240
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Embryonic/Neonatal medicine
Research InstitutionKurume University

Principal Investigator

OHYA Takashi  久留米大学, 医学部, 助教 (70333234)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
KeywordsNIRS / LFOs / trace alternant / TA-burst / Low frequency
Research Abstract

Low frequency oscillations (LFOs), which are defined as frequencies between 0.01-0.1 Hz, have increasingly recognized using monitoring cerebral blood flow, metabolism and function. Previous report ,which investigated NIRS and EEG in preterm infants, found pronouncing coherence between LFOs and burst activities during the trace alternant EEG phase. They concluded that NIRS-LFOs might be the consequence of BOLD phenomenon induced by oxygen consumption during burst activities. The aim of this study was to investigate the relationship between electro-cortical activities and NIRS-LFOs during every sleep stages in healthy neonates. We measured 13 records. The results were as below, we confirmed the correlation between electro-cortical activities and NIRS-LFOs, the power of NIRS-LFOs was observed every sleep stages. Because NIRS-LFOs occurred without electro-cortical activities, it suggested the existence of the origin of electro-cortical activities and LFOs in oxygen availability.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (3 results)

All 2013 2011

All Presentation (3 results)

  • [Presentation] 睡眠中の脳の神経活動がNIRSの変動に及ぼす影響の臨床的意義の検討2013

    • Author(s)
      大矢崇志、岩田欧介、山下裕史朗、生野貴洋、伊良皆啓治、松石豊次郎
    • Organizer
      第55回日本小児神経学会総会
    • Year and Date
      2013-05-30
    • Related Report
      2013 Final Research Report
  • [Presentation] 睡眠中の脳の神経活動がNIRSの変動に及ぼす影響の臨床的意義の検討2013

    • Author(s)
      大矢崇志
    • Organizer
      第55回日本小児神経学会学術集会
    • Place of Presentation
      大分オアシスタワーホテル 第7会場
    • Related Report
      2012 Research-status Report
  • [Presentation] 新生児睡眠時脳波とNIRSの同時計測解析2011

    • Author(s)
      松永淳,大矢崇志,岩田欧介,片山喜規,伊良皆啓治
    • Organizer
      平成23年度生体医工学会九州支部大会
    • Year and Date
      2011-01-08
    • Related Report
      2013 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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