Analysis of autoantibodies in pemphigus using phage display
Project/Area Number |
23791291
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Dermatology
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Research Institution | Keio University |
Principal Investigator |
YAMAGAMI Jun 慶應義塾大学, 医学部, 助教 (80327618)
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Project Period (FY) |
2011 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Keywords | 天疱瘡 / 自己抗体 / 自己免疫 / 自己免疫疾患 / 自己反応性B細胞 |
Research Abstract |
Pemphigus is an autoimmune bullous disease caused by autoantibodies against desmoglein (Dsg), an adhesion molecule between keratinocytes. In this study, we tried to investigate autoantibodies against the precursor form of Dsg (preDsg) and the pathogenicit
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Report
(3 results)
Research Products
(5 results)
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[Journal Article] Autoimmune reactivity against precursor form of desmoglein 1 in healthy Tunisians in the area of endemic pemphigus foliaceus2013
Author(s)
Toumi A, Saleh MA, Yamagami J, Abida O, Kallel M, Masmoudi A, Makni S, Turki H, Hachiya T, Kuroda K, Stanley JR, Masmoudi H, Amagai M
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Journal Title
J Dermatol Sci
Volume: 70(1)
Issue: 1
Pages: 19-25
DOI
Related Report
Peer Reviewed
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[Presentation] Antibodies against desmoglein 1 in healthy Tunisians in the area of endemic pemphigus foliaceus are mostly against the precursor molecule.2012
Author(s)
Toumi A, Saleh MA, Yamagami J, Abida O, Kallel M, Masmoudi A, Marki S, Turki H, Hachiya T, Kuroda K, Stanley JR, Masmoudi H, Amagai M
Organizer
The 75th Annual meeting of Society for Investigative Dermatology
Place of Presentation
ノースカロライナ州ローリー,米国)
Year and Date
2012-05-09
Related Report
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