Development of an automated melanoma discrimination system

• Project/Area Number: 23791295
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Dermatology
• Research Institution: Hosei University
• Principal Investigator: IYATOMI Hitoshi 法政大学, 理工学部, 准教授 (10386336)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 自動診断支援 / ダーモスコピー / メラノーマ / 画像解析 / 国際情報交流

Research Abstract

We developed a new automated melanoma discrimination system accommodating a wide variety of pigmented skin lesions including not only melanocytic skin lesions (MSLs), but also non-melanocytic skin lesions (noMSLs). Our new system was developed on a total 658 dermoscopy images (42 melanomas, 506 benign MSLs and 110 noMSLs) and achieved a sensitivity of 97.6% and a specificity of 92.2% under the leave-one-out cross-validation test.

Research Products

• [Journal Article] Extensionofautomatedmelanomascreeningfornon-melanocyticskinlesions (2013)
  • Author(s): KoheiShimizu,HitoshiIyatomi,M.EmreCelebiandKerri-AnnNorton
  • Journal Title: International Journal of Intelligent Systems Technologies and Applications
  • Peer Reviewed
• [Journal Article] 非侵 襲自律神経疾患計測のための外乱に強い電 子瞳孔計の開発 (2013)
  • Author(s): 鬼山 勝、彌冨 仁、尾川浩一
  • Journal Title: 電子情報通信学会論文誌 Volume: D-I, Vol.86, No.4 Pages: 867-875
  • NAID: 110009596334
  • Peer Reviewed
• [Journal Article] M.Emre.Celebi, Quan Wen, Sae Hwang, Hitoshi Iyatomi and Gerald Schaefer (2013)
  • Author(s): Lesion border detection in dermoscopy images using ensembles of thresholding methods
  • Journal Title: Skin Research and Technology Volume: 19,1 Issue: 1 Pages: 252-258
  • DOI: 10.1111/j.1600-0846.2012.00636.x
  • Peer Reviewed
• [Journal Article] Extension of automated melanoma screening for non-melanocytic skin lesions (2013)
  • Author(s): Kohei Shimizu, Hitoshi Iyatomi, M.Emre Celebi and Kerri-Ann Norton
  • Journal Title: International Journal of Intelligent Systems Technologies and Applications Volume: accepted
  • Peer Reviewed
• [Journal Article] Motion detection system accelerated by GPU for stereotactic radiosurgery (2013)
  • Author(s): Takuya Yamakawa, Koichi Ogawa, Hitoshi Iyatomi, Etsuo Kunieda, Keisuke Usui, Naoyuki Shigematsu
  • Journal Title: Medical Imaging Technology Volume: accepted
  • Peer Reviewed
• [Journal Article] Motion detection system with GPU acceleration for stereotactic radiosurgery (2012)
  • Author(s): Takuya Yamakawa, Koichi Ogawa, Hitoshi Iyatomi, Etsuo Kunieda, Keisuke Usui, Naoyuki Shigematsu
  • Journal Title: Medical Imaging Technology Volume: Vol.30, No.5 Pages: 268-278
  • NAID: 130002573588
  • URL: http://ci.nii.ac.jp/naid/130002573588
  • Peer Reviewed
• [Journal Article] An Automated Reconstruction Algorithm for Identification of 3D Architectures of Cribriform Ductal Carcinoma in Situ (2012)
  • Author(s): Kerri-Ann Norton, Sameera Namazi, Nicola Barnard, Mariko Fujibayashi, Gyan Bhanot, Shridar Ganesan, Hitoshi Iyatomi, Koichi Ogawa, and Troy Shinbrot
  • Journal Title: PLoS ONE Volume: Vol.7, No.9 Issue: 9 Pages: e44011-e44011
  • DOI: 10.1371/journal.pone.0044011
  • Peer Reviewed
• [Journal Article] Three-phase general border detection method for dermoscopy images using non-uniform illumination correction (2012)
  • Author(s): Kerri-Ann Norton, Hitoshi Iyatomi, M. Emre Celebi, Mizuki Sawada, Sumiko Ishizaki, Reiko Suzaki, Ken Kobayashi, Masaru Tanaka and Koichi Ogawa
  • Journal Title: Skin Research and Technology Volume: Vol.18, No.3 Issue: 3 Pages: 290-300
  • DOI: 10.1111/j.1600-0846.2011.00569.x
  • Peer Reviewed
• [Journal Article] Lesion border detection in dermoscopy images using ensembles of thresholding methods (2012)
  • Author(s): M.Emre.Celebi, Quan Wen, Sae Hwang, Hitoshi Iyatomi and Gerald Schaefer
  • Journal Title: Skin Research and Technology Volume: (accepted)
  • Peer Reviewed
• [Journal Article] 褥瘡重傷度と全身的予後の関係および臨床検査値と褥瘡予後の関係-1,134例の統計的検討- (2011)
  • Author(s): 石崎純子、彌冨 仁、町屋千鶴子、田中 勝
  • Journal Title: 東京女子医科大学雑誌 Volume: 81/2 Pages: 96-101
  • Peer Reviewed
• [Presentation] ファジィ推論ニューラルネットワークを用いたメラノーマ識別とルール抽出 (2013)
  • Author(s): 生馬悠史、彌冨 仁
  • Organizer: 2013 年電子情報通信学会総合大会
  • Place of Presentation: 岐阜大学、岐阜県
  • Year and Date: 2013-03-20
• [Presentation] 皮膚ダーモスコ ピー画像における経時変化定量のための位 置合わせ処理および色補正処理 (2013)
  • Author(s): 古正大二、彌冨 仁
  • Organizer: 2013 年電 子情報通信学会総合大会
  • Place of Presentation: 岐阜大学、岐阜県
  • Year and Date: 2013-03-20
• [Presentation] 3D Architecture of Ductal Carcinoma in Situ From Image Reconstructions (2012)
  • Author(s): Kerri-Ann Norton, Sameera Namazi, Nicola Barnard, Mariko Fujibayashi, Gyan Bhanot, Shridar Ganesan, Hitoshi Iyatomi, Koichi Ogawa, and Troy Shinbrot
  • Organizer: Proc. IEEE EMBS Conference on Biomedical Engineering (IECBES 2012)
  • Place of Presentation: Langkawi, Malaysia,
• [Presentation] Development of Robust Video-oculography System for Non-invasive Autonomic Nerve Quantification (2012)
  • Author(s): Masaru Kiyama, Hitoshi Iyatomi and Koichi Ogawa
  • Organizer: Proc. IEEE EMBS Conference on Biomedical Engineering (IECBES 2012)
  • Place of Presentation: Langkawi Malaysia
• [Presentation] Extension of automated melanoma screening for non-melanocytic skin lesions (2012)
  • Author(s): Kohei Shimizu, M.Emre Celebi, Kerri-Ann Norton and Hitoshi Iyatomi
  • Organizer: 19th International Conference on Mechatronics and Machine Vision in Practice (M2VIP12)
  • Place of Presentation: Auckland, New Zealand
• [Presentation] 尋常性乾癬の病 勢定量のための基礎的な検討 (2012)
  • Author(s): 向井一宏、彌冨 仁
  • Organizer: 第11回情報 科学技術フォーラム (FIT2012)
  • Place of Presentation: 法政大学、東京都
• [Presentation] ファジィ推論ニ ューラルネットワークを用いたメラノーマ 識別および識別ルールの自動生成 (2012)
  • Author(s): 生馬悠史、彌冨 仁
  • Organizer: 第103回 日本医学物理学会大会
  • Place of Presentation: パシフィコ横浜、神奈川県
• [Presentation] 3D Architecture of Ductal Carcinoma in Situ From Image Reconstructions (2012)
  • Author(s): Kerri-Ann Norton, Semeera Namazi, Mariko Fujibayashi, Shridar Ganesan, Nicola Barnard, Gyan Bhanot, Troy Shinbrot, Hitoshi Iyatomi, and Koichi Ogawa
  • Organizer: Proc. IEEE Biomedical Engineering and Science (IECBES 2012), pp.631-635
  • Place of Presentation: Langkawi, Malaysia
• [Presentation] Development of Robust Video-oculography System for Non-invasive Autonomic Nerve Quantification (2012)
  • Author(s): Masar Kiyama, Hitoshi Iyatomi, and Koichi Ogawa
  • Organizer: Proc. IEEE Biomedical Engineering and Science (IECBES 2012), pp.853-856
  • Place of Presentation: Langkawi, Malaysia
• [Presentation] Extension of automated melanoma screening for non-melanocytic skin lesions (2012)
  • Author(s): Kohei Shimizu, Hitoshi Iyatomi, Kerri-Ann Norton, and M.Emre Celebi
  • Organizer: Proc. 19th International Conference on Mechatronics and Machine Vision in Practice, pp.16-19
  • Place of Presentation: Auckland, New Zealand
• [Presentation] ファジィ推論ニューラルネットワークを用いたメラノーマ識別および識別ルールの自動生成 (2012)
  • Author(s): 生馬悠史、彌冨 仁
  • Organizer: 第103回 日本医学物理学会大会
  • Place of Presentation: パシフィコ横浜（神奈川県）
• [Presentation] Robust Video-oculography for Non-invasive Autonomic Nerve Quantification (2011)
  • Author(s): Masaru Kiyama, Hitoshi Iyatomi and Koichi Ogawa
  • Organizer: 33rd IEEE International Conference of the Engineering in Medicine and Bilology Society (EMBS 2011)
  • Place of Presentation: Boston, USA
• [Presentation] Feasibility Evaluation of a Motion Detection System with Face Images for Stereotactic Radiosurgery (2011)
  • Author(s): Takuya Yamakawa, Koichi Ogawa, Hitoshi Iyatomi and Etsuo Kunieda
  • Organizer: 33rd IEEE International Conference of the Engineering in Medicine and Bilology Society (EMBS 2011)
  • Place of Presentation: Boston, USA
• [Book] 医用画像工学ハンドブック (2012)
  • Author(s): 日本医用画像工学会
  • Publisher: PartII分担執筆
• [Book] 医用画像工学ハンドブック (2012)
  • Author(s): 尾川浩一 他多数
  • Publisher: 日本医用画像工学会
• [Remarks] メラノーマ自動診断支援サイト(皮膚科医向け)
  • URL: http://dermoscopy.k.hosei.ac.jp
• [Remarks]
  • URL: http://kenkyu-web.i.hosei.ac.jp/Profiles/20/0001921/theses.html