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New application of diffusion weighted imaging: Quantification of perfusion

Research Project

Project/Area Number 23791404
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionUniversity of Yamanashi

Principal Investigator

MOTOSUGI Utaroh  山梨大学, 医学工学総合研究部, 助教 (50377579)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
KeywordsMRI / 拡散強調像 / 磁気共鳴画像
Research Abstract

In this study, we studied new MR imaging technique using IVIM-DWI model to quantify not only diffusivity parameter of the proton but also perfusion parameter of the tissue. First, we evaluated the differences and variations of the ways of approximation to the model. As a result, we elucidated that the results of approximation using IVIM-DWI model can vary widely depending upon the way of approximation. In the preliminary study with clinical cases, we found that perfusion related parameter, D*, was well correlated with the renal function, which indicated the D* can reflect the renal perfusion. Conclusion: IVIM-DWI model can non-invasively estimate the perfusion related parameter.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (23 results)

All 2013 2012 2011 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results) Presentation (14 results) (of which Invited: 1 results) Remarks (2 results)

  • [Journal Article] Intravoxel incoherent motion imaging of the kidney: alterations in diffusion and perfusion in patients with renal dysfunction2013

    • Author(s)
      Ichikawa S, Motosugi U, Ichikawa T, Sano K, Morisaka H, Araki T.
    • Journal Title

      Magn Reson Imaging

      Volume: 31 Pages: 414-417

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 肝線維化診断 updata: MRIを用いたアプローチ-エラストグラフィだけじゃない-2013

    • Author(s)
      本杉宇太郎
    • Journal Title

      映像情報メディカル

      Volume: 45 Pages: 48-52

    • Related Report
      2012 Final Research Report
  • [Journal Article] 肝線維化診断 update: MRI を用いたアプローチ-エラストグラフィだけじゃない!-2013

    • Author(s)
      本杉宇太郎
    • Journal Title

      映像情報メディカル

      Volume: 45 Pages: 48-52

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Intravoxel incoherent motion imaging of focal hepatic lesions2012

    • Author(s)
      Ichikawa S, Motosugi U, Ichikawa T, Sano K, Morisaka H, Araki T
    • Journal Title

      J Magn Reson Imaging

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intravoxel Incoherent Motion(IVIM)イメージングにおけるb値の選択 サンプリング数とサンプリングパターンが再現性に与える影響.2012

    • Author(s)
      廣瀬準司, 本杉宇太郎, 佐野勝廣, 雨宮良治, 依田芳起.
    • Journal Title

      日本磁気共鳴医学会雑誌

      Volume: 32 Pages: 77-84

    • NAID

      10031046963

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intravoxel incoherent motion imaging of focal hepatic lesions.2012

    • Author(s)
      Ichikawa S
    • Journal Title

      J Magn Reson Imaging

      Volume: Epub Issue: 6 Pages: 1371-1376

    • DOI

      10.1002/jmri.23930

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intravoxel Incoherent Motion(IVIM)イメージングにおけるb値の選択 サンプリング数とサンプリングパターンが再現性に与える影響2012

    • Author(s)
      廣瀬 準司
    • Journal Title

      日本磁気共鳴医学会雑誌

      Volume: 32 Pages: 77-84

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Comparing the results of intravoxel incoherent motion diffusion-weighted imaging calculated by different estimation methods (展示発表)2013

    • Author(s)
      Motosugi U, Wakayama T, Ichikawa T, Araki T, Kakite S, Dyvorne H.
    • Organizer
      21thscientific meeting of ISMRM
    • Place of Presentation
      Salt Lake City, Utah, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Comparing the results of intravoxel incoherent motion diffusion-weighted imaging calculated by different estimation methods2013

    • Author(s)
      Motosugi U
    • Organizer
      International Society of Magnetic Resonance in Medicine
    • Place of Presentation
      Salt Lake Marriott Downtown at City Greek (Salt Lake City, USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Multi-b-value DWI of the body: IVIM imaging2012

    • Author(s)
      本杉宇太郎
    • Organizer
      第40回日本磁気共鳴医学会大会(シンポジウム 1,Bodydiffusion)
    • Place of Presentation
      国立京都国際会館(京都市)
    • Related Report
      2012 Final Research Report
  • [Presentation] Intravoxel Incoherent Motion (IVIM)-DWI による肝の潅流評価:食事による門脈血流の変化.2012

    • Author(s)
      佐藤祐一,本杉宇太郎,廣瀬準司,雨宮良治.
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Related Report
      2012 Final Research Report
  • [Presentation] Intravoxel Incoherent Motion (IVIM)-DWI による 肝の潅流評価: 食事による門脈血流の変化2012

    • Author(s)
      佐藤祐一
    • Organizer
      日本磁気共鳴医学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Multi-b-value DWI of the body: IVIM imaging (シンポジウム)2012

    • Author(s)
      本杉宇太郎
    • Organizer
      日本磁気共鳴医学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Intravoxel incoherent motion imaging of the liver: Which affects more on apparent diffusion coefficient changes of cirrhosis and liver lesions, D or D*?2012

    • Author(s)
      Ichikawa S
    • Organizer
      International Society of Magnetic Resonance in Medicine
    • Place of Presentation
      Melbourne Convention and Exhibition Center (Melbourne, Australia)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Intravoxel Incoherent Motion Diffusion-weighted Imaging for Distinguishing between Malignant and Benign Hepatic Focal Liver Lesions.2011

    • Author(s)
      Ichikawa S, Motosugi U, Ichikawa T, Sano , Sou H, Muhi A, Araki T.
    • Organizer
      The 97thScientific Assembly and Annual Meeting of Radiological Society of North America (RSNA)
    • Place of Presentation
      Chicago, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] 肝腫瘤における Intravoxel Incoherent Motion (IVIM)-DWI:良悪性の鑑別.2011

    • Author(s)
      市川新太郎,本杉宇太郎,市川智章,佐野勝廣,曹博信,ムヒアリ,池長聰,熊谷博司,荒木力.
    • Organizer
      第39回日本磁気共鳴医学会大会.
    • Place of Presentation
      リーガロイヤル小倉(北九州市)
    • Related Report
      2012 Final Research Report
  • [Presentation] Intravoxel Incoherent Motion (IVIM) イメージングにおける b 値の選択に関する検討 : b 値サンプリング数とサンプリングパターンが再現性に与える影響2011

    • Author(s)
      廣瀬準司,本杉宇太郎,佐野勝廣,雨宮良治.
    • Organizer
      第39回日本磁気共鳴医学会大会.
    • Place of Presentation
      リーガロイヤル小倉(北九州市)
    • Related Report
      2012 Final Research Report
  • [Presentation] 腎Intravoxel Incoherent Motion (IVIM)-DWIの初期検討

    • Author(s)
      市川新太郎,本杉宇太郎,市川智章,佐野勝廣,曹博信,池長聰,熊谷博司,荒木力
    • Organizer
      第70回日本医学放射線学会総会
    • Place of Presentation
      Web開催
    • Related Report
      2011 Research-status Report
  • [Presentation] 肝腫瘤におけるIVIM-DWI: 良悪性の鑑別

    • Author(s)
      市川新太郎,本杉宇太郎,市川智章,佐野勝廣,曹博信,池長聰,熊谷博司,荒木力
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      リーガロイヤルホテル小倉(北九州市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 腎機能低下とIVIM-DWI: 拡散制限と潅流

    • Author(s)
      市川新太郎,本杉宇太郎,市川智章,佐野勝廣,曹博信,池長聰,熊谷博司,荒木力
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      リーガロイヤルホテル小倉(北九州市)
    • Related Report
      2011 Research-status Report
  • [Presentation] IVIM-DWI for Distinguishing between

    • Author(s)
      Shintaro Ichikawa, Utaroh Motosugi, et al.
    • Organizer
      97th Annual Meeting of RSNA
    • Place of Presentation
      マコーミックプレイス(シカゴ)
    • Related Report
      2011 Research-status Report
  • [Remarks]

    • URL

      http://yamarad.umin.ne.jp/ivim/

    • Related Report
      2012 Final Research Report
  • [Remarks] 拡散強調像の新たな展開

    • URL

      http://yamarad.umin.ne.jp/ivim/index.html

    • Related Report
      2012 Annual Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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