| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Research Abstract |
To elucidate function of bHLH transcriptional factor Olig2, gene expression pattern of fetal spinal cords between wild type mice and Olig2 knock-out mice was investigated with DNA subtraction method. Twelve genes were identified as candidates of downstream factors of Olig2 and expression patterns of theses genes were examined. Peroxiredoxin 1 was expressed specifically in the location of motoneurons, and was presumed to concern with differentiation for motoneurons.
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