| Project/Area Number |
23791882
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Niigata University |
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Principal Investigator |
KUBOTA Yamato 新潟大学, 医歯学総合病院, 助教 (40547593)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Keywords | 聴覚医学 / 中枢聴覚 / イメージング / 大脳聴覚野 / 周波数マップ / 中枢性耳鳴 / 耳鳴 |
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| Research Abstract |
We studied the cerebral auditory cortex function in mice using flavoprotein fluorescence imaging method.As a result,we got the following findings.1:After continuous tonal sonud exposure,On and Off responces in A1 were strongly observed.2:Changing the direction of frequency modulation of stimuli,specific reactions were observed at UF and DP area.It had been projected from the site that is different from the primary auditory cortex in the medial geniculate body.3:Age-related hearing loss mouse,there was no apparent change in the auditory cortex map in moderate hearing loss.Activities in midrange stimuli had become strong when it comes to severe hearing loss.4:In both sides measurement,strong responces were observed in the contralateral auditory cortex of the stimulus side in the auditory cortex.
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