| Project/Area Number |
23792136
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Functional basic dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
INUI Chizuko (YAMAMOTO Chizuko) 大阪歯科大学, 歯学部, 助教 (00419459)
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| Research Collaborator |
YAMAMOTO Takashi 畿央大学, 健康科学部, 教授 (60028793)
UEDA Katsura 大阪歯科大学, 歯学部, 講師 (50448106)
NAKATSUKA Michiko 大阪歯科大学, 歯学部, 講師 (70368158)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 加齢 / 味覚嗜好性 / 味細胞 / 味神経 / 鼓索神経 / 脳機能 / 二瓶法 / 脳 / 神経 |
|---|
| Research Abstract |
It remains unclear how aging affect food preferences. Thus, we investigated the age-related changes in taste palatability, and neural mechanisms of those changes. Behavioral studies using rats revealed that taste sensitivity was higher in older age than younger rats. We also found that aging cause shift in palatability of sweet, umami and bitter taste solutions. These behavioral changes were not due to alteration in morphology of taste cells and the electrophysiological responses of taste nerve. Therefore, it is suggested that age-related changes in taste sensitivity and palatability are accounted for by development of central nervous system rather than peripheral.
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