The age-related changes in taste transduction and perception mechanisms
| Project/Area Number |
23792136
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Functional basic dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
INUI Chizuko (YAMAMOTO Chizuko) 大阪歯科大学, 歯学部, 助教 (00419459)
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| Research Collaborator |
YAMAMOTO Takashi 畿央大学, 健康科学部, 教授 (60028793)
UEDA Katsura 大阪歯科大学, 歯学部, 講師 (50448106)
NAKATSUKA Michiko 大阪歯科大学, 歯学部, 講師 (70368158)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 加齢 / 味覚嗜好性 / 味細胞 / 味神経 / 鼓索神経 / 脳機能 / 二瓶法 / 脳 / 神経 |
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| Research Abstract |
It remains unclear how aging affect food preferences. Thus, we investigated the age-related changes in taste palatability, and neural mechanisms of those changes. Behavioral studies using rats revealed that taste sensitivity was higher in older age than younger rats. We also found that aging cause shift in palatability of sweet, umami and bitter taste solutions. These behavioral changes were not due to alteration in morphology of taste cells and the electrophysiological responses of taste nerve. Therefore, it is suggested that age-related changes in taste sensitivity and palatability are accounted for by development of central nervous system rather than peripheral.
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Report
(3 results)
Research Products
(37 results)
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[Presentation] 加齢による味覚嗜好性の変化2011
Author(s)
乾(山本)千珠子,上田甲寅,山本隆,中塚美智子,安春英,隈部俊二,岩井康智
Organizer
日本味と匂学会第45回大会
Place of Presentation
石川県立音楽堂
Year and Date
2011-10-06
Related Report
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[Presentation] 加齢が味覚嗜好性に及ぼす影響2011
Author(s)
乾(山本)千珠子,上田甲寅,山本隆,中塚美智子,安春英,隈部俊二,岩井康智
Organizer
第53回歯科基礎医学会
Place of Presentation
長良川国際会議場
Year and Date
2011-10-02
Related Report
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