| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Research Abstract |
This study showed that chlorhexidine-gluconate disrupted individual biofilm-forming Porphyromonas gingivalis cells, which is a major pathogen in marginal periodontitis and refractory periapical periodontitis, but did not destroy the biofilms, and the constituents derived from disrupted cells were maintained in the biofilm.Moreover, it is suggested that proteins are the major contributors to the integrity of the residual biofilms.
|
