Evaluation of bone regeneration using the hybrid materials of autogenous plasma and bone marrow mesenchimal stem cells
| Project/Area Number |
23792324
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
MARUKAWA Eriko 東京医科歯科大学, 大学院・医歯学総合研究科, 講師 (40419263)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 自己血漿 / 幹細胞 / 骨再生 / 血漿 / fibrin / 骨髄間葉系幹細胞 / 骨髄穿刺液 |
|---|
| Research Abstract |
This study evaluated the effect of autogenous plasma and platelet-released growth factors to bone formation. PPP, PRP and PRF were implanted to each extraction socket in canine mandible. The amount of new bone formation was the highest in the PPP group, PPP and PRF could sufficiently maintain the bone width and height of the socket. β-TCP with bone marrow aspirate concentrate was implanted into the back muscle of dogs. This study indicated that BMAC comprises concentrated bone marrow stem cells and a fibrin scaffold that has the ability to induce ectopic bone formation
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Report
(3 results)
Research Products
(14 results)
