Development of novel bone regeneration method of applying the three-dimensional technology

• Project/Area Number: 23792367
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Surgical dentistry
• Research Institution: Nagoya City University
• Principal Investigator: KOHGO Tomoyuki 名古屋市立大学, 医学(系)研究科(研究院), 研究員 (30566211)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 骨再生 / 3次元足場材料 / 間葉系幹細胞 / 三次元テクノロジー / 足場

Research Abstract

Bone regeneration was possible by the use of mesenchymal stem cells in the application of new three-dimensional scaffold material, but as a method of bone regeneration for the larger bone defects, solve the problem of the physical properties of the scaffold material was required. It was confirmed that due to the increased bone regeneration capacity is higher with the new three-dimensional scaffold material (platelet rich plasma) properties of the scaffold.

Research Products

• [Journal Article] Platelet-rich fibrin has a healing effect on chemotherapy-induced mucositis in hamsters. (2014)
  • Author(s): Horii Kouichirou
  • Journal Title: Oral Surgery, Oral Medicine, Oral Radiology and Endodontology Volume: 4 Issue: 4 Pages: 445-453
  • DOI: 10.1016/j.oooo.2013.12.004
  • Peer Reviewed
• [Journal Article] Bone regeneration with self-assembling Peptide nanofiber scaffolds in tissue engineering for osseointegration of dental implants. (2012)
  • Author(s): Tomoyuki Kohgo, Yoichi Yamada, Kenji Ito, Akihiro Yajima, Ryoko Yoshimi, Kazuto Okabe, Syunsuke Baba, Minoru Ueda
  • Journal Title: The international journal of periodontics & restorative dentistry Volume: 31
  • Peer Reviewed
• [Journal Article] Bone regeneration with self-assembling Peptide nanofiber scaffolds in tissue engineering for osseointegration of dental implants (2011)
  • Author(s): Kohgo T, Yamada Y, Ito K, Yajima A, Yoshimi R, Okabe K, Baba S, Ueda M
  • Journal Title: The international journal of periodontics & restorative dentistry Volume: 31(4) Pages: 9-16
• [Presentation] Crestal Approach Sinus Augmentation with Platelet-rich Fibrin (PRF) in Pneumatized Maxilla : A reviw of 12 cases (2012)
  • Author(s): Tomoyuki Kohgo
  • Organizer: 2012 Academy of Ossointegration Phoenix Arizona
  • Place of Presentation: USA Arizona Convention Center 2^<nd>
  • Year and Date: 2012-03-02
• [Presentation] Crestal Approach Sinus Augmentation with Platelet-rich Fibrin (PRF) in Pneumatized Maxilla: A reviw of 12 cases. (2012)
  • Author(s): Tomoyuki Kohgo, Takeo Kanayama, Yuko Hokimoto, Toshio Shigetomi, Motoo Yokoi
  • Organizer: 2012 Academy of Ossointegration
  • Place of Presentation: Arizona Convention Center（USA）