| Project/Area Number |
23792666
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Lifelong developmental nursing
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| Research Institution | Iwate Medical University |
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Principal Investigator |
CHIBA Takeshi 岩手医科大学, 薬学部, 助教 (80552926)
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| Research Collaborator |
TAKAHASHI Katsuo 岩手医科大学, 名誉教授 (50453296)
MORIMOTO Yasunori 城西大学, 薬学部, 教授 (90001057)
UEDA Hideo 城西大学, 薬学部, 准教授 (50326998)
KIMURA Soichiro 城西大学, 薬学部, 助教 (30433650)
INOUE Noriaki 岩手医科大学, 薬学部
YAEGASHI Ayaka 岩手医科大学, 薬学部
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 乳腺 / 母乳 / セロトニン / 選択的セロトニン再取り込み阻害剤 / β-カゼイン / スクリーニング / ヒト乳腺上皮細胞 / MCF-12A / セロトニン再取り込み阻害剤 / 乳腺上皮細胞 / プロラクチン |
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| Research Abstract |
Breastfeeding has many benefits for both infants and mothers. However, if one medication taken by mothers during pregnancy and lactation influences the specific function of mammary gland, optimal breastfeeding might be disturbed. It is therefore important to determine whether a drug influences its function or not. We show in the present study that our cell culture model using MCF-12A is useful to assess the effects of therapeutic drugs on the mammary function in human.
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