| Project/Area Number |
23890095
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Immunology
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
ISE Masako (KOHYAMA Masako) 大阪大学, 微生物病研究所, 特任研究員(常勤) (70311339)
|
|---|
| Project Period (FY) |
2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | リンパ球 / 自然免疫 / 免疫監視 |
|---|
| Research Abstract |
Red pulp macrophage(RPM) is a tissue macrophage which localized in spleen. Spi-C is a transcriptional factor that control RPM development. We made Spi-C IRES-GFP knock-in mouse and Spi-C conditional knockout mice. We identified cells that had a potential to differentiate into RPMs. And also, we found the factor, one of the metabolite of red blood cell, which could induce Spi-C expression
|
