Development of autologous scaffolds
| Project/Area Number |
24300177
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|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | National Institute for Materials Science |
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Principal Investigator |
CHEN Guoping 独立行政法人物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, ユニット長 (50357505)
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| Co-Investigator(Renkei-kenkyūsha) |
KAWAZOE Naoki 物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, MANA研究者 (90314848)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2014: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2012: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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|---|
| Keywords | マトリックス / 足場材料 / 三次元細胞培養 / 鋳型法 / 脱細胞化 / 多孔質構造 / 生体親和性 |
|---|
| Outline of Final Research Achievements |
A method to prepare cultured cells derived extracellular matrix scaffolds was developed by using three-dimensional cell culture and template method. Various cell types can be used for preparation of their respective extracellular matrix scaffolds. Autologous extracellular matrix scaffolds prepared from autologous cells showed excellent biocompatibility without eliciting adverse inflammatory and immune responses when being implanted. The scaffolds will be useful for control the functions of stem cells and for regenerative medicine.
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Report
(4 results)
Research Products
(31 results)
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[Book] World Scientific2013
Author(s)
Guoping Chen, Takashi Hoshiba, Naoki Kawazoe
Total Pages
13
Publisher
Tissue Regeneration: Where Nano-Structures Meets Biology
Related Report
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