Regulation of bone remodeling surrounding implant by low-content hydrogen DLC
| Project/Area Number |
24390434
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
NIKAWA Hiroki 広島大学, 医歯薬保健学研究院, 教授 (10228140)
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| Co-Investigator(Kenkyū-buntansha) |
TAJI Tsuyoshi 広島大学, 大学院医歯薬保健学研究(歯), 准教授 (80284214)
峯 裕一 広島大学, 医歯薬保健学研究院, 特任助教 (60605989)
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| Co-Investigator(Renkei-kenkyūsha) |
NAKATANI Tatsuyuki 岡山理科大学, 技術科学研究所, 教授 (50520920)
KEISHI Okamoto トーヨーエイテック株式会社, 表面処理事業部企画開発課, 課長 (90507724)
MAKIHIRA Seicho 九州大学, 大学院歯学研究院, 准教授 (80304450)
MINE Yuichi 広島大学, 大学院医歯薬保健学研究院, 特任助教 (60605989)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
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| Keywords | DLC / インプラント / 骨リモデリング / 破骨細胞 / 骨芽細胞 |
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| Outline of Final Research Achievements |
It is necessary to develop the novel fixture considering the strong osseointegration and bone remodeling for success of dental implant treatment. We investigated the effects of DLC-treated Ti disks (DLC-Ti) including low amount of hydrogen on osteoblast and osteoclast differentiation in vitro.
This study suggests that specific-hydrogen content of DLC-Ti can affect response of osteoblast and osteoclast cells. In future, specific-hydrogen content of DLC-Ti may be useful for the material of dental implants that gives good prognosis.
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Report
(4 results)
Research Products
(8 results)
